Afinitor
Warnings
What may interact with Afinitor ?
Do not take this medicine with any of the following medications:
-live virus vaccines
This medicine may interact with the following medications:
-antiviral medicines for HIV or AIDS
-aprepitant
-certain antibiotics like erythromycin or clarithromycin
-certain medicines for cholesterol like simvastatin
-certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
-cyclosporine
-dexamethasone
-certain medicines for blood pressure, heart disease, irregular heart beat like diltiazem, nicardipine, and verapamil
-certain medicines for fungal infections like fluconazole, itraconazole, ketoconazole, and voriconazole
-grapefruit juice
-nefazodone
-rifabutin
-rifampin
-telithromycin
What should I tell my health care provider before I take Afinitor ?
They need to know if you have any of these conditions:
-diabetes
-heart disease
-high cholesterol
-immune system problems
-infection (especially a virus infection such as chickenpox, cold sores, or herpes)
-kidney disease
-liver disease
-low blood counts, like low white cell, platelet, or red cell counts
-recent or ongoing radiation
-rare hereditary problems of galactose intolerance, the Lapp lactase deficiency, or glucose-galactose malabsorption
-an unusual or allergic reaction to everolimus, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding
What should I watch for while using Afinitor ?
This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop. Visit your doctor or health care professional for regular check-ups. You may need regular tests to monitor possible side effects of the drug.
This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.
Before having surgery, talk to your health care provider to make sure it is ok. This drug can increase the risk of poor healing of your surgical site or wound. You will need to stop using Afinitor for 1 week before surgery. After surgery, wait at least 2 weeks before restarting this drug. Make sure the surgical site or wound is healed enough before restarting this drug. Talk to your health care provider if questions.
Do not become pregnant while taking this medicine or for 8 weeks after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 4 weeks after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 2 weeks after stopping it.
This medicine has caused ovarian failure in some women and reduced sperm counts in some men. This medicine may interfere with the ability to have a child. You should talk with your doctor or health care professional if you are concerned about your fertility.
This medicine has caused reduced sperm counts in some men. This may interfere with the ability to father a child. You should talk to your doctor or health care professional if you are concerned about your fertility.
Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body''s ability to fight infections. Try to avoid being around people who are sick.
This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.
If you have had a kidney transplant, immediately tell your doctor if your incision site is red, warm, or painful. Also, tell your doctor if your incision site opens up or swells or if contains blood, fluid, or pus.
Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
Where should I keep my medicine?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.
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