Do not take this medicine with the following medication:

-dasabuvir; ombitasvir; paritaprevir; ritonavir
-ombitasvir; paritaprevir; ritonavir
-vaginal lubricants or other vaginal products that are oil-based or silicone-based
This medicine may also interact with the following medications:

-acetaminophen
-antibiotics or medicines for infections, especially rifampin, rifabutin, rifapentine, and griseofulvin, and possibly penicillins or tetracyclines
-aprepitant or fosaprepitant
-armodafinil
-ascorbic acid (vitamin C)
-barbiturate medicines, such as phenobarbital or primidone
-bosentan
-certain antiviral medicines for hepatitis, HIV or AIDS
-certain medicines for cancer treatment
-certain medicines for seizures like carbamazepine, clobazam, felbamate, lamotrigine, oxcarbazepine, phenytoin, rufinamide, topiramate
-certain medicines for treating high cholesterol
-cyclosporine
-dantrolene
-elagolix
-flibanserin
-grapefruit juice
-lesinurad
-medicines for diabetes
-medicines to treat fungal infections, such as griseofulvin, miconazole, fluconazole, ketoconazole, itraconazole, posaconazole or voriconazole
-mifepristone
-mitotane
-modafinil
-morphine
-mycophenolate
-St. John''s wort
-tamoxifen
-temazepam
-theophylline or aminophylline
-thyroid hormones
-tizanidine
-tranexamic acid
-ulipristal
-warfarin

They need to know if you have any of these conditions:

-abnormal vaginal bleeding
-blood vessel disease or blood clots
-breast, cervical, endometrial, ovarian, liver, or uterine cancer
-diabetes
-gallbladder disease
-having surgery
-heart disease or recent heart attack
-high blood pressure
-high cholesterol or triglycerides
-history of irregular heartbeat or heart valve problems
-kidney disease
-liver disease
-migraine headaches
-protein C deficiency
-protein S deficiency
-recently had a baby, miscarriage, or abortion
-stroke
-systemic lupus erythematosus (SLE)
-tobacco smoker
-an unusual or allergic reaction to estrogens, progestins, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor or health care professional for regular checks on your progress. You will need a regular breast and pelvic exam and Pap smear while on this medicine.
Check with your doctor or health care professional to see if you need an additional method of contraception during the first cycle that you use this ring. Male condoms (made with natural rubber latex, polyisoprene, and polyurethane) and spermicides may be used. Do not use a diaphragm, cervical cap, or a female condom, as it is unknown if this ring can interfere with these birth control methods and their proper placement.
If you have any reason to think you are pregnant, stop using this medicine right away and contact your doctor or health care professional.
If you are taking this medicine for hormone related problems, it may take several cycles of use to see improvement in your condition.
Smoking increases the risk of getting a blood clot or having a stroke while you are using hormonal birth control, especially if you are more than 35 years old. You are strongly advised not to smoke.
Some women are prone to getting dark patches on the skin of the face (chloasma). Your risk of getting chloasma with this medicine is higher if you had chloasma during a pregnancy. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.
This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.
If you are going to have elective surgery, you may need to stop using this medicine before the surgery. Consult your health care professional for advice.
This medicine does not protect you against HIV infection (AIDS) or any other sexually transmitted diseases.

Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Between each cycle of use, wash and dry the ring as directed and store in the case. Throw away any unused medicine after the expiration date. The ring should be placed in the case after 13 cycles (1 year) of use and discarded via a drug take-back option, if available. If not, then discard in the trash out of reach of children and pets. Do NOT flush down the toilet.