Common Questions about Bupropion (Wellbutrin)

What is the difference between Wellbutrin XL and Wellbutrin SR?

Wellbutrin XL is the brand name of bupropion extended-release, and Wellbutrin SR is the brand name of bupropion sustained release. The extended-release version of bupropion releases the medicine slowly into the body, meaning the drug will stay in the system longer. These two formulations are not interchangeable.

How long does it take bupropion to work?

You probably will not feel any improvement for several weeks. It’s very likely that you will feel the side effects before you see an improvement in your mood. That’s why it is important to take bupropion regularly and exactly as prescribed. However, if the side effects become too bothersome, you should let your doctor know.

When should I start taking bupropion for seasonal depression?

Bupropion extended-release (Wellbutrin XL) is approved to treat seasonal depression. You can begin treatment in autumn (prior to the start of symptoms), continue through winter, and discontinue in early spring. Talk to your doctor in the spring on how to safely taper off bupropion. You should not discontinue bupropion suddenly, as you can experience unpleasant withdrawal symptoms.

Can I take bupropion during pregnancy?

It is not known if bupropion may harm an unborn baby. Though limited, there is some data showing that bupropion can affect the development of the unborn baby’s heart. Discuss with your doctor if you plan to get pregnant. You should not start or stop bupropion without consulting your doctor first; your doctor will be able to evaluate the risks and the benefits of bupropion with you. Untreated depression during pregnancy can lead to preterm birth, low birth weight, and other adverse outcomes.

What is the price of bupropion without insurance?

Without insurance, bupropion can be as high as $138.99, but with a free BuzzRx prescription discount coupon, you could pay as low as $9.64 for the most common version of this medication. Use the BuzzRx drug price lookup tool to find the lowest discounted price and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions of bupropion like Wellbutrin. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.

What is the price of bupropion with insurance?

Ask your pharmacist or insurance provider for your copay price on bupropion—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins. 

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for bupropion. When using the BuzzRx lookup tool to find the price of your medication, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.