What side effects may I notice from receiving Climara Pro?

Side effects that you should report to your doctor or health care professional as soon as possible:
-breakthrough bleeding and spotting
-breast tissue changes or discharge
-chest pain
-leg, arm or groin pain
-nausea, vomiting
-severe headaches
-severe stomach pain
-sudden shortness of breath
-yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-changes in sexual desire
-mood changes, anxiety, depression, frustration, anger, or emotional outbursts
-increased or decreased appetite
-skin rash, acne, or brown spots on the skin
-symptoms of vaginal infection like itching, irritation or unusual discharge
-weight gain

This list may not describe all possible side effects for Climara Pro. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.