What side effects may I notice from receiving COMETRIQ?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-bloody or black, tarry stools
-breathing problems
-changes in vision
-chest pain or chest tightness
-confusion, trouble speaking or understanding
-feeling faint or lightheaded, falls
-jaw pain, especially after dental work
-red or dark-brown urine
-redness, swelling, or sores on hands or feet
-severe headaches
-shortness of breath, chest pain, swelling in a leg
-spitting up blood or brown material that looks like coffee grounds
-stomach pain
-sudden numbness or weakness of the face, arm or leg
-sweating
-swelling of the ankles, feet, hands
-trouble swallowing
-trouble walking, dizziness, loss of balance or coordination
-unusual bruising or bleeding from the eye, gums, or nose
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-diarrhea
-loss of appetite
-nausea, vomiting
-sore throat
-weight loss

This list may not describe all possible side effects for COMETRIQ. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.