What side effects may I notice from receiving Estradiol, Norethindrone?

Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breast tissue changes or discharge
-changes in vision
-chest pain
-confusion, trouble speaking or understanding
-dark urine
-general ill feeling or flu-like symptoms
-light-colored stools
-nausea, vomiting
-pain, swelling, warmth in the leg
-right upper belly pain
-severe headaches
-shortness of breath
-sudden numbness or weakness of the face, arm or leg
-trouble walking, dizziness, loss of balance or coordination
-unusual vaginal bleeding
-yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-acne
-brown spots on the face
-change in appetite
-change in sexual desire
-depressed mood or mood swings
-fluid retention and swelling
-stomach cramps or bloating
-unusually weak or tired
-weight gain

This list may not describe all possible side effects for Estradiol, Norethindrone. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.