What side effects may I notice from receiving EstroGel?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breast lumps, tissue changes, or discharge
-high blood pressure
-migraines or severe, sudden headaches
-signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
-signs and symptoms of a blood clot such as breathing problems; changes in vision or speech; chest pain; severe, sudden headache; pain, swelling, warmth in the leg; trouble speaking; sudden numbness or weakness of the face, arm or leg
-swelling in your ankles, legs, or feet
-unusual vaginal bleeding

Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

-breast tenderness or pain
-hair loss
-mild headache
-nausea, vomiting
-upset stomach

This list may not describe all possible side effects for EstroGel. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.