What side effects may I notice from receiving Estrostep Fe?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions such as skin rash or itching, hives, swelling of the lips, mouth, tongue, or throat
-breast tissue changes or discharge
-dark patches of skin on your forehead, cheeks, upper lip, and chin
-depression
-high blood pressure
-migraines or severe, sudden headaches
-signs and symptoms of a blood clot such as breathing problems; changes in vision; chest pain; severe, sudden headache; pain, swelling, warmth in the leg; trouble speaking; sudden numbness or weakness of the face, arm or leg
-stomach pain
-symptoms of vaginal infection like itching, irritation or unusual discharge
-yellowing of the eyes or skin
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

-acne
-breast pain, tenderness
-irregular vaginal bleeding or spotting, particularly during the first month of use
-mild headache
-nausea
-weight gain (slight)

This list may not describe all possible side effects for Estrostep Fe. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.