Etodolac (Lodine) Uses

Etodolac is used to relieve pain, swelling, and stiffness in the joints caused by osteoarthritis and rheumatoid arthritis. The immediate-release tablets may be used to treat acute pain (short-term). The extended-release tablets can be prescribed to treat juvenile arthritis in children. 

There may be additional uses of etodolac—your doctor or pharmacist can give you further drug information.

Etodolac (Lodine) Mechanism of Action

Etodolac is a non-steroidal anti-inflammatory drug. It works by blocking the formation of substances called prostaglandins in the body, which cause pain and inflammation.

Etodolac (Lodine) Doses

Etodolac is available in the following dosage forms:

• Immediate-release tablet 400 mg
• Extended-release tablets 400 mg, 500 mg, and 600 mg 
• Capsules 200 mg and 300 mg

You should use the lowest effective dose of etodolac for the shortest duration to treat your condition. The usual dose of etodolac is as follows:

• For acute pain: 200 to 400 mg every 6-8 hours. Maximum dose 1,000 mg per day. 
• For osteoarthritis and rheumatoid arthritis: 300 mg 2-3 times a day or 400 mg to 500 mg twice daily. The dose may be lowered to 600 mg once daily after symptoms are controlled. The maximum dose is 1,000 mg daily.

The dose of etodolac extended-release tablets in children with juvenile arthritis will depend on the child’s body weight.