Etonogestrel-Ethinyl Estradiol

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jul 23, 2024

Pharmacist Tips


Etonogestrel and Ethinyl Estradiol (NuvaRing) Tips from Pharmacists

  • It is important to follow the recommended schedule of 3 weeks in and 1 week out for contraceptive efficacy. Set a reminder in your phone to help you remember to take the vaginal ring out after 3 weeks and insert a new one a week later.

  • You will have withdrawal bleeding 2-3 days after you remove the contraceptive ring. Insert a new ring exactly one week after you remove the previous one even if your bleeding hasn’t stopped.

  • If you do not get withdrawal bleeding, i.e., you miss your period, you could be pregnant. If you have used the contraceptive ring as directed, do a pregnancy test after two consecutive missed periods. If you left the ring out for more than 3 hours or had a break of longer than one week, do a pregnancy test after one missed period.

  • It is common to have some light spotting or breakthrough bleeding, especially in the first 3 months. Tell your doctor if you have severe or persistent abnormal vaginal bleeding.

  • Tell your doctor if you develop depression, mood changes, or a new headache pattern while using the vaginal ring.

  • Take precautions to protect yourself from sexually transmitted infections, including HIV infection.