Warnings


What may interact with Cyclosporine, Modified?

Do not take this medicine with any of the following medications:
-bosentan
-cidofovir
-cisapride
-mibefradil
-ranolazine
-red yeast rice, monascus purpureus
-St. John''s wort
-tacrolimus

This medicine may also interact with the following medications:
-acyclovir
-allopurinol
-amiloride
-amiodarone
-bromocriptine
-carbamazepine
-certain antibiotics
-cimetidine
-colchicine
-danazol
-digoxin
-female hormones, including contraceptive or birth control pills
-imatinib
-medicines for fungal infections like amphotericin B, fluconazole, itraconazole, terbinafine, and ketoconazole
-medicines for blood pressure like diltiazem, nicardipine, verapamil, enalapril, ramipril, and losartan
-medicines for cholesterol like lovastatin, simvastatin, atorvastatin, and fenofibrate
-medicines for HIV infection like indinavir, nelfinavir, ritonavir, and saquinavir
-medicines that suppress the immune system
-melphalan
-methotrexate
-metoclopramide
-NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen
-octreotide
-orlistat
-oxcarbazepine
-phenobarbital
-phenytoin
-ranitidine
-sirolimus
-spironolactone
-steroid medicines like prednisone or cortisone
-sulfinpyrazone
-ticlopidine
-triamterene
-vaccines
-voriconazole

What should I tell my health care provider before I take Cyclosporine, Modified?

They need to know if you have any of these conditions:
-cancer
-high blood pressure
-immune system problems
-infection
-kidney disease
-liver disease
-previous coal tar, PUVA, ultraviolet, or radiation therapy
-an unusual or allergic reaction to cyclosporine, alcohol, corn oil (Neoral only), castor oil, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast feeding

What should I watch for while using Cyclosporine, Modified?

Visit your doctor or health care professional for regular checks on your progress. You will have regular blood checks. Do not change the brand of medicine unless directed by your doctor or health care professional.

If you get a cold or other infection while receiving this medicine, call your doctor or health care professional. Do not treat yourself. The medicine may decrease your body''s ability to fight infections.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine can make you more sensitive to the sun. Keep out of the sun. If you cannot avoid being in the sun, wear protective clothing and use sunscreen. Do not use sun lamps or tanning beds/booths.

The medicine can cause unusual growth of gum tissue and can make your gums bleed. Practice good oral hygiene, and be careful when brushing and flossing your teeth. See your dentist regularly.

Some products may contain alcohol. Ask your pharmacist or healthcare provider if this medicine contains alcohol. Be sure to tell all healthcare providers you are taking this medicine. Certain medicines, like metronidazole and disulfiram, can cause an unpleasant reaction when taken with alcohol. The reaction includes flushing, headache, nausea, vomiting, sweating, and increased thirst. The reaction can last from 30 minutes to several hours.

Where should I keep my medicine?

Keep out of the reach of children.

Store Neoral between 20 and 25 degrees C (68 and 77 degrees F).

Store Gengraf between 15 and 30 degrees C (59 and 86 degrees F).

Keep the medicine in the original packaging. Throw away any unused medicine after the expiration date.