What side effects may I notice from receiving Lupron Depot?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-chest pain
-depression or memory disorders
-pain in your legs or groin
-pain at site where injected or implanted
-seizures
-severe headache
-signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision
-swelling of the feet and legs
-suicidal thoughts or other mood changes
-visual changes
-vomiting
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-breast swelling or tenderness
-decrease in sex drive or performance
-diarrhea
-hot flashes
-loss of appetite
-muscle, joint, or bone pains
-nausea
-redness or irritation at site where injected or implanted
-skin problems or acne

This list may not describe all possible side effects for Lupron Depot. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.