This medicine may interact with the following medications:

-certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
-rifampin

They need to know if you have any of these conditions:

-dehydration
-kidney disease
-mental illness
-an unusual or allergic reaction to apremilast, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Patients and their families should watch out for new or worsening depression or thoughts of suicide. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, call your health care professional.

Check with your doctor or health care professional if you get an attack of severe diarrhea, nausea and vomiting, or if you sweat a lot. The loss of too much body fluid can make it dangerous for you to take this medicine.

Keep out of the reach of children.

Store below 30 degrees C (86 degrees F). Throw away any unused medicine after the expiration date.