This medicine may interact with the following medications:

-digoxin
-medicines that increase the risk of thrombosis like estrogens or erythropoietic agents (e.g., epoetin alfa and darbepoetin alfa)
-warfarin

They need to know if you have any of these conditions:

-blood clots in the legs or the lungs
-high blood pressure
-high cholesterol
-infection
-irregular monthly periods or menstrual cycles
-kidney disease
-liver disease
-smoke tobacco
-thyroid disease
-an unusual or allergic reaction to lenalidomide, thalidomide, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

You may need blood work done while you are taking this medicine.

This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.

This medicine is available only through a special program. Doctors, pharmacies, and patients must meet all of the conditions of the program. Your health care provider will help you get signed up with the program if you need this medicine. Through the program you will only receive up to a 28 day supply of the medicine at one time. You will need a new prescription for each refill.

This medicine can cause birth defects. Do not get pregnant while taking this drug. Females with child-bearing potential will need to have 2 negative pregnancy tests before starting this medicine. Pregnancy testing must be done every 2 to 4 weeks as directed while taking this medicine. Use 2 reliable forms of birth control together while you are taking this medicine and for 4 weeks after you stop taking this medicine. If you think that you might be pregnant talk to your doctor right away. Do not breast-feed an infant while taking this medicine.

Men must use a latex condom during sexual contact with a woman while taking this medicine and for 4 weeks after you stop taking this medicine. A latex condom is needed even if you have had a vasectomy. Contact your doctor right away if your partner becomes pregnant. Do not donate sperm while taking this medicine and for 4 weeks after you stop taking this medicine.

Do not give blood while taking the medicine and for 4 weeks after completion of treatment to avoid exposing pregnant women to the medicine through the donated blood.

Talk to your doctor about your risk of cancer. You may be more at risk for certain types of cancers if you take this medicine.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.