Do not take this medicine with any of the following medications:

-alfuzosin
-apalutamide
-certain medicines for irregular heart beat like amiodarone, bepridil, dofetilide, dronedarone, flecainide, propafenone, quinidine
-cobicistat
-conivaptan
-elagolix
-eletriptan
-eliglustat
-enzalutamide
-eplerenone
-ergot alkaloids like dihydroergotamine, ergonovine, ergotamine, methylergonovine
-flibanserin
-idelalisib
-isavuconazonium
-ivabradine
-lomitapide
-lovastatin
-lurasidone
-meperidine
-naloxegol
-pergolide
-pimozide
-ranolazine
-red yeast rice
-rifampin
-silodosin
-simvastatin
-St. John''s wort
-terfenadine
-tinidazole
-tolvaptan
-triazolam
-voriconazole

This medicine may also interact with the following medications:

-atovaquone
-bedaquiline
-bosentan
-birth control pills, patches, rings, or injections
-certain medicines for blood pressure, heart disease, irregular heart beat like digoxin, disopyramide, lidocaine, mexiletine, metoprolol, timolol
-certain medicines for cancer like dasatinib, ibrutinib, nilotinib, venetoclax, vinblastine, vincristine
-certain medicines for cholesterol like atorvastatin, rosuvastatin
-certain medicines for depression, anxiety, or psychotic disturbances amitriptyline, bupropion, desipramine, fluoxetine, nefazodone, nortriptyline, paroxetine, perphenazine, quetiapine, risperidone, thioridazine, trazodone
-certain medicines for erectile dysfunction like avanafil, sildenafil, tadalafil, vardenafil
-certain medicines for fungal infections like fluconazole, itraconazole, posaconazole
-certain medicines for seizures like carbamazepine, clonazepam, ethosuximide, divalproex, lamotrigine, phenytoin
-certain medicines for sleep like buspirone, clorazepate, diazepam, estazolam, flurazepam, zolpidem
-certain medicines that treat or prevent blood clots like warfarin, rivaroxaban
-clarithromycin
-colchicine
-cyclosporine
-dronabinol
-methamphetamine
-metronidazole
-narcotic medicines for pain
-other antivirals for HIV
-quinine
-rifabutin
-salmeterol
-simeprevir
-sirolimus
-steroid medicines like betamethasone, budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone, mometasone, prednisolone, triamcinolone
-tacrolimus
-theophylline

They need to know if you have any of these conditions:

-diabetes
-hemophilia
-high cholesterol or triglycerides
-liver disease
-an unusual or allergic reaction to ritonavir, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor or health care provider for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.

HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control. Women who can still have children must use a reliable form of barrier contraception, like a condom or diaphragm.

This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.

Keep out of the reach of children.

Store this medicine at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Throw away any unused medicine after the expiration date.