What side effects may I notice from receiving TUKYSA?

Side effects that you should report to your doctor or health care professional as soon as possible:

-diarrhea
-signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

-joint pain
-nausea, vomiting
-mouth sores
-pain, tingling, numbness in the hands or feet
-rash
-signs and symptoms of low red blood cells or anemia such as unusually weak or tired; feeling faint or lightheaded; falls; breathing problems

This list may not describe all possible side effects for TUKYSA. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.