Do not take this medicine with any of the following medications:

-artemether
-certain antivirals for HIV or hepatitis such as atazanavir, daclatasvir, doravirine, elbasvir; grazoprevir, fostemsavir, lopinavir, nelfinavir, paritaprevir, rilpivirine, ritonavir, and tipranavir
-certain medicines for fungal infections such as isavuconazonium and voriconazole
-lonafarnib
-lorlatinib
-lurasidone
-praziquantel
-ranolazine
This medicine may also interact with the following medications:

-alfentanil
-certain medicines for seizures such as carbamazepine, phenobarbital, phenytoin
-clopidogrel
-cyclosporine
-ergot alkaloids such as dihydroergotamine, ergotamine
-fentanyl
-gemfibrozil
-midazolam
-omeprazole
-pimozide
-quinidine
-rifabutin
-rifampin
-rifapentine
-St. John''s Wort
-sirolimus
-tacrolimus
-warfarin

They need to know if you have any of these conditions:

-bone problems
-brain tumor
-head injury
-heart disease
-high blood pressure
-high cholesterol
-stroke
-seizures
-an unusual or allergic reaction to enzalutamide, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your health care provider for regular checks on your progress. Tell your health care provider if your symptoms do not start to get better or if they get worse.
This medicine should not be used in women. Men should not father a child while taking this medicine and for 3 months after stopping it. There is potential for serious harm to an unborn child. Talk to your health care provider for more information.

Keep out of the reach of children and pets.
Store between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture. Keep the container tightly closed. Get rid of any unused medicine after the expiration date.
To get rid of medicines that are no longer needed or have expired:

-Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put it in the trash, empty the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.