How Much Is Levothyroxine Without Insurance?

Have you been prescribed levothyroxine for the treatment of hypothyroidism (underactive thyroid gland)? If you don’t have prescription drug coverage in your health insurance plan, you might be wondering: What is the cash price of levothyroxine? The price of levothyroxine depends on various factors. You can expect to pay anywhere from $12 for 30 tablets of generic levothyroxine 25-micrograms (mcg) to as much as $270 for 90 tablets of brand name Synthroid 137-mcg. Find out the difference between an underactive thyroid vs overactive thyroid.

Please continue reading to learn more about the cost of levothyroxine without insurance. We will also include some other information that can help patients save money on levothyroxine and other medications.

What Is Levothyroxine?

Levothyroxine is a synthetic form of thyroid hormone T4. Thyroid hormones play a role in many important functions in the body. If you have a condition called hypothyroidism (underactive thyroid gland), your thyroid gland does not make enough thyroid hormone. Check out these 8 signs you may have a thyroid condition.

If your healthcare provider determines that you do have an underactive thyroid, you may be prescribed levothyroxine to treat hypothyroidism. This medicine is also used to treat thyroid cancer, along with surgery and radioactive iodine therapy. Learn more about hypothyroidism vs hyperthyroidism.

Expert Recommended Further Reading

Search For Savings On Your Thyroid Medication

What Is The Average Price of Levothyroxine?

The cost of thyroid medicine can range from as little as $12 per month to over $270 per month, depending on various factors, such as whether you’re taking generic drugs or brand name versions, the dose, and other factors. For example, the cost of levothyroxine at Walgreens is $19.23 for a 1-month supply (30 tablets) of the 25 mcg dose with a free BuzzRx discount coupon.

Whether you’re buying generic levothyroxine or brand-name thyroid medication, you can save money on your thyroid medication with a free BuzzRx discount coupon:

What Factors Affect The Price of Levothyroxine (Thyroid Hormone Replacement)?

If you don’t have insurance coverage for prescription drugs, the price you pay for levothyroxine will depend on various factors. For example, levothyroxine 50 mcg price may be lower than levothyroxine 100 mcg price or levothyroxine 125 mcg price. In addition to dosage, other factors also play a role. The cost of levothyroxine 100 mcg may be different for different dosage forms. Moreover, the cost of levothyroxine at Walgreens may be different from that at CVS or other pharmacy chains.

Here’s an overview of the different factors that can affect the price you pay for levothyroxine if you don’t have insurance coverage for prescription drugs:

Dose (levothyroxine is available in various doses ranging from 25 mcg to 300 mcg)
Dosage form (oral tablet, capsule, liquid suspension)
Number of pills (the per-pill costs may be lower when you get a 90-day supply versus a 30-day supply)
Generic drug versus brand name medication (brand names are more expensive than the generic version - see below for reasons)
Your location
The pharmacy you use
Price fluctuations due to supply chain issues

Is Levothyroxine Covered by Insurance?

Generic levothyroxine is covered by most private and employer-sponsored health insurance plans. The exact cost you’ll pay for levothyroxine will depend on your specific plan. You can also check your plan’s formulary to see if any brand names (for example, Synthroid) are covered.

How Much Does Levothyroxine Cost With Insurance?

The price of levothyroxine with insurance depends on your specific insurance plan with prescription drug coverage. Private insurance typically lowers the out-of-pocket cost of levothyroxine. However, levothyroxine prices can still vary depending on deductibles, copays, and formulary placement.

Why is Levothyroxine Not Covered by Medicare?

Levothyroxine is usually covered by Medicare, but full coverage may not be provided in certain situations, depending on the specific Medicare plan and individual circumstances. For example, Medicare may not cover your levothyroxine prescription cost if there are questions about the necessity of this medication, for instance, if you have subclinical hypothyroidism (slightly elevated TSH with normal thyroid hormone levels).

How Much Does Levothyroxine Cost With Medicare?

All Medicare Part D and Medicare Advantage prescription drug plans cover levothyroxine. But how much you will pay for levothyroxine out-of-pocket will depend on the stage of coverage you are in.

Medicare Coverage Stage	Levothyroxine Cost
Pre-deductible	You may have to pay the full levothyroxine price out-of-pocket.
Post-deductible	You will pay the copay (typically free to $1), and the plan will cover the rest of the levothyroxine cost.
Donut hole (coverage gap)	There is a temporary limit on what Medicare will pay for your prescription, so you may have higher levothyroxine costs out-of-pocket.
Post donut hole	Medicare typically covers most of the cost of your thyroid medication.

What Is The Price of Levothyroxine 25 mcg?

The price of levothyroxine 25 mcg depends on generics versus brand name versions, the quantity purchased, and whether you are using any levothyroxine coupons. Purchasing a 90-day supply can make levothyroxine more affordable in terms of unit price. For example, 90 tablets of the 25-mcg strength may retail at $27, thereby lowering the unit price of your thyroid medicine by 25% from $0.40 to $0.30.

Here are some estimated retail prices for levothyroxine 25 mcg:

Generic levothyroxine 25 mcg 30 tablets: $11.99 retail price, $10.45 with a free coupon from BuzzRx
Generic levothyroxine 25 mcg 90 tablets: $26.89 retail price, $12.36 with a free levothyroxine coupon from BuzzRx
Synthroid brand 25 mcg 30 tablets: $65.91 retail price, $55.27 with a free BuzzRx levothyroxine coupon
Synthroid brand 25 mcg 90 tablets: $191.62 retail price, $151.82 with a free levothyroxine BuzzRx coupon

Compare the best prescription discounts of 2025.

How Much Is A Private Prescription For Levothyroxine?

The price of levothyroxine without insurance can vary from pharmacy to pharmacy. Here are some estimated retail prices for levothyroxine at major pharmacy chains:

Generic Levothyroxine Price

Dose	Number of Tablets	Price Range
25 mcg	30 tablets	$11.99 to $14.35
25 mcg	90 tablets	$26.89 to $31.97
88 mcg	30 tablets	$11.99 to $16.99
88 mcg	90 tablets	$35.19 to $38.89
200 mcg	30 tablets	$16.99
200 mcg	180 tablets	$77.79

Brand Name Thyroid Medication Prices

Brand	Dose	Number of Pills	Price
Euthyrox	25 mcg	30 tablets	$22.99
Levo-T	25 mcg	30 tablets	$34.43 to $35.59
Levoxyl	25 mcg	30 tablets	$44.49
Synthroid	25 mcg	30 tablets	$65.91 to $78.80
Unithroid	25 mcg	30 tablets	$140.92 to $144.20
Tirosint	25 mcg	30 tablets	$165.99 to $172.9
Ermeza solution	150 mcg/5 mL		$148.53 to $149.35

Cost Comparison: Levothyroxine vs Other Thyroid Medications

Uninsured patients can expect to pay the following for levothyroxine vs other thyroid replacement medicines:

Name and Dose of Thyroid Medicine	BuzzRx Discounted Price
Levothyroxine 50 mcg price	$13.97 for 90 tablets at Rite-Aid
Levothyroxine 100 mcg price	$14.89 for 90 tablets at Safeway
Levothyroxine 125 mcg price	$22.30 for 90 tablets at Publix
Levoxyl 25 mcg price	$13.58 for 90 tablets at Safeway
Synthroid 25 mcg price	$35.20 for 90 tablets at Fry’s
Synthroid 88 mcg price	$37.62 for 90 tablets at Fry’s
Unithroid 25 mcg price	$13.20 for 90 tablets at Publix
Levo-T 25 mcg price	$13.58 for 90 tablets at Safeway
Euthyrox 25 mcg price	$13.58 for 90 tablets at Randalls
Tirosint 25 mg price	$448.35 for 90 capsules at Walgreens
Ermeza oral solution 150 mcg/5 mL	$184.17 for 90 doses at CVS
Thyquidity oral solution 100 mcg/5 mL	$153.15 for 90 doses at Walmart

Visit the BuzzRx Coupon Page to get the best levothyroxine prices and discounted prices on brand-name thyroid drugs.

How Much Does A 90-Day Supply of Synthroid Cost With Insurance?

The cost of a 90-day supply of Synthroid depends on the dose, dosage form, and other factors such as your location and the pharmacy chain you use. Estimated retail prices for the Synthroid brand range between $190 and $270 for 90 tablets.

You can save on the costs of brand name Synthroid by obtaining your medication through the Synthroid Delivers Program website. Your pharmacist can give you more information, but you will pay $75 for a 90-day supply, $54 for a 60-day supply, and $29.50 for a 30-day supply of your Synthroid prescription.

The program allows you to pay a fixed cash price without the hassles of insurance coverage or prior authorization. The price does not change based on the dose you’re prescribed, so Synthroid 100 mcg price and Synthroid 125 mcg price are the same.

Additionally, you avoid price fluctuations or the pressure to substitute other brand names or generic versions for Synthroid. The Synthroid Delivers Program also offers a free 2-day home delivery for the first prescription and other services such as refill reminders, access to their pharmacy team, and education about your thyroid disorder.

Why Is There A Price Difference Between A Synthroid Prescription And The Generic Drug?

When a pharmaceutical company develops a new medication, it takes many years of research and clinical trials to ensure its safety and efficacy. To recover some of the costs of research and development, testing, marketing, and other expenses, the company applies for a patent. This patent gives them the rights to sell the medicine exclusively at a price set by them. That is why brand name forms of drugs such as Synthroid are more expensive than generics such as levothyroxine.

What Is The Price of Synthroid 100 mcg vs 125 mcg?

There isn’t a big difference between the retail price of Synthroid 100 mcg vs 125 mcg. The price of Synthroid 100 mcg and Synthroid 125 mcg can be as low as $55 to $71 at different pharmacies for a 1-month supply (30 tablets) using a BuzzRx discount coupon.

You may pay a lower price for Synthroid with a BuzzRx discount coupon compared to the cost of Synthroid with insurance, depending on your copay.

In addition, if you are concerned about the cost of Synthroid vs levothyroxine (brand name vs generic), a BuzzRx discount coupon can help you save money on the brand name medication.

Do I Have to Pay for Levothyroxine?

You have to pay for levothyroxine if you do not have health insurance or you do not have prescription drug coverage under your health insurance plan. However, if you are insured and have coverage for prescription drugs, you may pay a lower price for levothyroxine or you may not have to pay for levothyroxine out of pocket at all. Please check your specific plan for details.

How Much Should I Pay for Levothyroxine?

How much you pay for levothyroxine will depend on the treatment plan (dose prescribed), your insurance coverage, and the pharmacy you use.

How Much Is Synthroid Without Insurance?

The cost of Synthroid without insurance depends on the dose, number of tablets purchased, and other factors, such as the pharmacy you choose. Generally speaking, you can expect to pay around $66 to $79 for 30 tablets of Synthroid 25 mcg. A BuzzRx Synthroid discount coupon can help you make savings on your prescription.

What Is The Cost of Synthroid With Insurance?

The cost of Synthroid with insurance depends on your specific insurance plan, whether Synthroid is on your insurance plan’s formulary, and other factors such as the dose of Synthroid prescribed.

How Much Is a 30-Day Supply of Levothyroxine?

The cost of a 30-day supply of levothyroxine without insurance varies. On average, 30 tablets of 25 mcg or 50 mcg generic levothyroxine cost around $12 to $13.

How Much is Levothyroxine Without Insurance?

The price of levothyroxine without insurance starts at around $12 for 30 tablets of the 25-mcg dose of generic levothyroxine. The levothyroxine price may be higher for different dosages and/or dosage forms and can vary from pharmacy to pharmacy.

Why Is Levothyroxine So Cheap?

Once the patent on a brand name drug developed by a pharmaceutical company expires, others can manufacture and market the generic medicine (for example, levothyroxine) without repeating the research and testing conducted by the manufacturer of Synthroid brand. This is why levothyroxine and generics of other drugs are much cheaper than the brand name versions. A generic contains the same active ingredient and is equally effective and safe, but is usually considerably cheaper than the brand name medication.

Check out “Understanding levothyroxine side effects.”

How To Save Money On Levothyroxine?

If you are having trouble paying for your thyroid medicines, there are several ways to make them more affordable:

Check your insurance coverage to see if prescription drugs are covered.
Talk to your doctor about taking generic levothyroxine instead of brand name medication.
Request free samples from your healthcare professional.
Compare prices at different pharmacies.
Visit BuzzRx.com and get free levothyroxine coupons (a free coupon can help you save up to 80% on your prescriptions).
Check if you qualify for enrollment in the Synthroid Delivers Program.

Learn more about thyroid medication at our blog, “What are the signs my thyroid medication is not working?