What side effects may I notice from receiving GAVRETO?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-chest pain
-confusion
-cough
-dizziness
-fever
-headache
-increase in blood pressure
-signs and symptoms of bleeding such as bloody or black, tarry stools; red or dark brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eyes, gums, or nose
-signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
-signs and symptoms of tumor lysis syndrome like vomiting, shortness of breath, seizures, muscle pain, and/or muscle weakness
Side effects that usually do not require medical attention (report these to your doctor or health care professional if they continue or are bothersome):

-constipation
-diarrhea
-dry mouth
-joint pain
-tiredness

This list may not describe all possible side effects for GAVRETO. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.