Hydrocodone-Homatropine (Hycodan) Uses

The combination of hydrocodone and homatropine is used to relieve cough.

There may be other uses of hydrocodone-homatropine—your pharmacist or doctor can give you further drug information.

Hydrocodone-Homatropine (Hycodan) Mechanism of Action

Hydrocodone is a narcotic opioid. Its exact mechanism of action is unclear, but it is believed that it acts directly on the cough center in the brain and suppresses the urge to cough. Homatropine blocks the muscarinic action of acetylcholine, thereby relaxing the airways and reducing mucus secretion.

Hydrocodone-Homatropine (Hycodan) Doses

This medication comes in the form of a tablet containing 5 mg hydrocodone bitartrate and 1.5 mg homatropine methylbromide. It also comes as an oral solution (syrup) containing 5 mg of hydrocodone bitartrate and 1.5 mg of homatropine methylbromide per 5 mL. 

The recommended dose of Hycodan (hydrocodone-homatropine) is 1 tablet or 5 mL of the oral solution every 4-6 hours as needed to relieve cough. The maximum dose is 6 tablets or 30 mL in 24 hours.