Acetaminophen-Codeine

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: May 22, 2023

Pros & Cons


Acetaminophen-Codeine Pros and Cons

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  • The combination of acetaminophen and codeine is effective in providing pain relief for mild to moderate pain severity. 
  • It combines two medications in one pill for convenience.
  • A liquid form of this pain medicine is available if you have trouble swallowing pills.
  • There is a lower-cost generic available.

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  • You need to take acetaminophen-codeine every 4 hours or so for effective pain control.
  • Pain relievers such as acetaminophen and codeine contain an opioid medicine, which can be habit-forming.
  • This combination is not recommended during pregnancy or breastfeeding.