Drug Details

Acetaminophen

( Arthritis Pain Relief )

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Aug 09, 2022

acetaminophen Drug Details (Generic)

Generic Name:

Acetaminophen

Common Brands:

Mapap Arthritis Pain, Tylenol, Tylenol Arthritis Pain, Acephen, Actamin, Feverall, Tempra Quicklets, Panadol

Availability:

Over-the-counter

Therapeutic Class:

Analgesic and antipyretic

Forms:

Tablets, chewable tablets, extended-release tablets, orally disintegrating tablets, capsules, solution, powder, suppositories

Administration:

By mouth, by insertion into the rectum (suppositories)

Therapeutic Uses:

Headache
Pain from menstrual periods
Backache
Muscle aches
Toothache
Pain relief for cold/flu
Pain relief from arthritis
Fever

Controlled Status:

Not a controlled substance

Acetaminophen Drug Class

Acetaminophen (ah set a mee noe fen) is an analgesic (pain reliever) and antipyretic (fever reducer).

Acetaminophen Age Range

Acetaminophen is approved for use in adults and children.

Tylenol Drug Details (Brand)

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Infants' Pain and Fever Drug Details (Brand)

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Children's Pain-Fever Relief Drug Details (Brand)

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Mapap Arthritis Pain Drug Details (Brand)

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Therapeutic Class:

Pain Relief

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OTC

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Oral tablet, extended release

ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever.

8HR Muscle Aches-Pain Drug Details (Brand)

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Tylenol 8 Hour Drug Details (Brand)

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Infants' Pain Relief Drug Details (Brand)

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Pain Relief ES (acetaminophen) Drug Details (Brand)

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Tylenol Extra Strength Drug Details (Brand)

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Pain Relief

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OTC

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Oral tablet

ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever.

MAXrelief junior Drug Details (Brand)

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Acetaminophen Pain Relief Drug Details (Brand)

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Pharbetol Drug Details (Brand)

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Therapeutic Class:

Pain Relief

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OTC

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Oral tablet

ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever.

Children's Non-Aspirin Drug Details (Brand)

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Aphen Drug Details (Brand)

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Infant Pain Reliever Drug Details (Brand)

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Infant's Pain Relief Drug Details (Brand)

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Non-Aspirin Drug Details (Brand)

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M-PAP Drug Details (Brand)

Generic Name:

Therapeutic Class:

Pain Relief

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OTC

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Form:

Oral solution

ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever.

Ed-APAP Drug Details (Brand)

Generic Name:

Therapeutic Class:

Pain Relief

Availability:

OTC

Common Brands:

Form:

Oral solution

ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever.

Children's Pain Reliever Drug Details (Brand)

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Oral suspension

Ofirmev Drug Details (Brand)

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Little Remedies Fever and Pain Drug Details (Brand)

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Child Fever Reducer-Pain Relvr Drug Details (Brand)

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Oral suspension

Pain Reliever ES(acetaminophn) Drug Details (Brand)

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Children's Fever Reducing Drug Details (Brand)

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Acetaminophen Extra Strength Drug Details (Brand)

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Arthritis Pain Reliever Drug Details (Brand)

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Oral tablet, extended release|Topical gel

Children's Aurophen Pain-Fever Drug Details (Brand)

Generic Name:

Therapeutic Class:

Pain Relief

Availability:

OTC

Common Brands:

Form:

Oral suspension

ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever.

Aminofen Drug Details (Brand)

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Shake That Ache Drug Details (Brand)

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Non-Aspirin Extra Strength Drug Details (Brand)

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Tylenol Arthritis Pain Drug Details (Brand)

Generic Name:

Therapeutic Class:

Pain Relief

Availability:

OTC

Common Brands:

Form:

Oral tablet, biphasic release

ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever.

Infant Fever Reducer-Pain Relf Drug Details (Brand)

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Silapap Drug Details (Brand)

Generic Name:

Therapeutic Class:

Pain Relief

Availability:

OTC

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Form:

Oral solution

ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever.

Mapap (acetaminophen) Drug Details (Brand)

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BetaTemp Drug Details (Brand)

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Children's Tylenol Drug Details (Brand)

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Pain Relief Adult Drug Details (Brand)

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Infant's Acetaminophen Drug Details (Brand)

Generic Name:

Therapeutic Class:

Pain Relief

Availability:

OTC

Common Brands:

Form:

Oral suspension

ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever.

KinderMed Kids Pain-Fever Drug Details (Brand)

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8 Hour Pain Reliever Drug Details (Brand)

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Non-Aspirin Pain Relief Drug Details (Brand)

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Oral tablet

Children's Mapap Drug Details (Brand)

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Therapeutic Class:

Pain Relief

Availability:

OTC

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Form:

Chewable tablet|Oral disintegrating tablet

ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever.

KinderMed Infants Pain-Fever Drug Details (Brand)

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Children's Pain Relief Drug Details (Brand)

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Chewable tablet

Pain Relief (acetaminophen) Drug Details (Brand)

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Child Pain Rel-Fever Reducer Drug Details (Brand)

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PediaCare Fever Reducer Drug Details (Brand)

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Feverall Drug Details (Brand)

Generic Name:

Therapeutic Class:

Pain Relief

Availability:

OTC

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Form:

Rectal suppository

ACETAMINOPHEN (a set a MEE noe fen) is a pain reliever. It is used to treat mild pain and fever.

Pain Reliever (acetaminophen) Drug Details (Brand)

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Children's Acetaminophen Drug Details (Brand)

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Oral solution|Oral suspension

Athenol Drug Details (Brand)

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Arthritis Pain Relief (acetam) Drug Details (Brand)

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acetaminophen Uses (Generic)

Acetaminophen Uses

Acetaminophen is an antipyretic and analgesic. It is used for fever and pain such as menstrual pain, backache, muscle aches, headache, dental pain, pain from a common cold or flu, and minor pain from arthritis.

There may be other uses of acetaminophen—your doctor or pharmacist can give you further drug information.

Acetaminophen Mechanism of Action

Acetaminophen prevents the synthesis of prostaglandins in the body. Prostaglandins are natural substances that cause fever and pain.

Acetaminophen Doses

Acetaminophen is available in many dosage forms. The dose of acetaminophen depends on your age, the condition you are treating, and the formulation of the medicine you are using (tablets, extended-release tablets, capsules, liquid, powder, or suppositories).

In adults, the usual dose of acetaminophen is 650 mg by mouth every 4-6 hours as needed. The maximum daily dose of acetaminophen in adults is 3,000 to 4,000 mg per day. Check the package label for the correct dose. Some tablets contain 325 mg of acetaminophen, while others contain 500 mg or 650 mg.

In children, the dose of acetaminophen depends on the child’s weight. Children may be given acetaminophen chewable tablets or liquid. Before giving a child acetaminophen, you should check how much of the medicine is in the tablet or liquid, for example, 80 mg tablet or 160 mg/5 mL liquid. Children over the age of 12 years can usually take the adult dose, but it’s best to check with the child’s healthcare provider.

acetaminophen Directions (Generic)

How To Use Acetaminophen

Acetaminophen is available in various forms to take by mouth and as rectal suppositories. You can take acetaminophen by mouth with or without food. Check the package label or prescription label carefully and take this medicine as directed.

If you have been prescribed acetaminophen, follow the instructions on your prescription label and use acetaminophen exactly as directed by your doctor. Do not take a higher or lower dose of this medicine or take it more or less frequently than what your doctor tells you.

If you are giving acetaminophen to a child, you should know that adult acetaminophen should not be given to children. Read the package label carefully to ensure that the acetaminophen product is suitable for children. Check the dosing instructions carefully for children's acetaminophen products to ensure you do not exceed the maximum dose.

Many combination products contain acetaminophen, for example, those used to provide relief of pain from sore throat, cold, and flu. Read the package labels to ensure that the cumulative dose from all the products combined does not exceed the maximum dose. Taking too much acetaminophen or more than the recommended maximum dose can lead to severe liver damage.

Do not cut, crush, dissolve or chew the extended-release tablets of acetaminophen - swallow them whole.

If you are taking an acetaminophen tablet that has a score line, you may swallow the whole or split tablet after you cut the medication evenly.

If you are taking liquid medication (an oral suspension of acetaminophen), shake the bottle well before use. Use dosing devices (a cup or syringe) to measure the dose of liquid acetaminophen accurately.

Missed dose: If you are taking acetaminophen on a regular basis and miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and take the next dose according to your regular dosing schedule. Do not take a double dose to make up for a missed dose.

Storage: Store acetaminophen at room temperature (between 15-30° C or 59-86° F) away from moisture, heat, and direct light in a tightly closed container. Do not store medications in the bathroom, where they can be exposed to moisture and heat. Keep all medications safely out of reach of children and pets.

Unused medicine: Unused acetaminophen should be disposed of in a way that children, other people, and pets cannot get to them. Do not throw acetaminophen in the trash or flush it down the toilet. The best way to dispose of expired or unneeded acetaminophen is through a drug take-back program. Learn more about proper medication disposal.

NOTE: This medication guide is a summary and may not contain all possible drug information on acetaminophen. The information contained here may not be up-to-date. This sheet is for information purposes only. If you have questions about acetaminophen, talk to your doctor or pharmacist for medical advice.

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Tylenol Directions (Brand)

Infants' Pain and Fever Directions (Brand)

Children's Pain-Fever Relief Directions (Brand)

Mapap Arthritis Pain Directions (Brand)

How should I use Acetaminophen?

Take this medicine by mouth with a glass of water. Follow the directions on the package or prescription label. Do not cut, crush or chew this medicine. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 12 years of age for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of Acetaminophen contact a poison control center or emergency room at once. NOTE: Acetaminophen is only for you. Do not share Acetaminophen with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

8HR Muscle Aches-Pain Directions (Brand)

Tylenol 8 Hour Directions (Brand)

Infants' Pain Relief Directions (Brand)

Pain Relief ES (acetaminophen) Directions (Brand)

Tylenol Extra Strength Directions (Brand)

How should I use Tylenol Extra Strength?

Take this medicine by mouth with a glass of water. Follow the directions on the package or prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 6 years of age for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of Tylenol Extra Strength contact a poison control center or emergency room at once. NOTE: Tylenol Extra Strength is only for you. Do not share Tylenol Extra Strength with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

MAXrelief junior Directions (Brand)

Acetaminophen Pain Relief Directions (Brand)

Pharbetol Directions (Brand)

How should I use Acetaminophen?

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Children's Non-Aspirin Directions (Brand)

Aphen Directions (Brand)

Infant Pain Reliever Directions (Brand)

Infant's Pain Relief Directions (Brand)

Non-Aspirin Directions (Brand)

M-PAP Directions (Brand)

How should I use Acetaminophen?

Take this medicine by mouth. This medicine comes in more than one concentration. Check the concentration on the label before every dose to make sure you are giving the right dose. Follow the directions on the package or prescription label. Use a specially marked spoon or dropper to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years old for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Ed-APAP Directions (Brand)

How should I use Acetaminophen?

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Children's Pain Reliever Directions (Brand)

Ofirmev Directions (Brand)

Little Remedies Fever and Pain Directions (Brand)

Child Fever Reducer-Pain Relvr Directions (Brand)

Pain Reliever ES(acetaminophn) Directions (Brand)

Children's Fever Reducing Directions (Brand)

Acetaminophen Extra Strength Directions (Brand)

Arthritis Pain Reliever Directions (Brand)

Children's Aurophen Pain-Fever Directions (Brand)

How should I use Acetaminophen?

Take this medicine by mouth. This medicine comes in more than one concentration. Check the concentration on the label before every dose to make sure you are giving the right dose. Follow the directions on the package or prescription label. Shake well before using. Use a specially marked spoon or dropper to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years of age for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Aminofen Directions (Brand)

Shake That Ache Directions (Brand)

Non-Aspirin Extra Strength Directions (Brand)

Tylenol Arthritis Pain Directions (Brand)

How should I use Tylenol Arthritis Pain?

Overdosage: If you think you have taken too much of Tylenol Arthritis Pain contact a poison control center or emergency room at once. NOTE: Tylenol Arthritis Pain is only for you. Do not share Tylenol Arthritis Pain with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Infant Fever Reducer-Pain Relf Directions (Brand)

Silapap Directions (Brand)

How should I use Acetaminophen?

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Mapap (acetaminophen) Directions (Brand)

BetaTemp Directions (Brand)

Children's Tylenol Directions (Brand)

Pain Relief Adult Directions (Brand)

Infant's Acetaminophen Directions (Brand)

How should I use Acetaminophen?

Take this medicine by mouth. This medicine comes in more than one concentration. Check the concentration on the label before every dose to make sure you are giving the right dose. Follow the directions on the package or prescription label. Shake well before using. Use a specially marked spoon or dropper to measure each dose. Ask your pharmacist if you do not have one. Household spoons are not accurate. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years of age for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

KinderMed Kids Pain-Fever Directions (Brand)

8 Hour Pain Reliever Directions (Brand)

Non-Aspirin Pain Relief Directions (Brand)

Children's Mapap Directions (Brand)

How should I use Acetaminophen?

Take this medicine by mouth. Chew it completely before swallowing. Follow the directions on the package or prescription label. Take your medicine at regular intervals. Do not take your medicine more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 2 years of age for selected conditions, precautions do apply.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

KinderMed Infants Pain-Fever Directions (Brand)

Children's Pain Relief Directions (Brand)

Pain Relief (acetaminophen) Directions (Brand)

Child Pain Rel-Fever Reducer Directions (Brand)

PediaCare Fever Reducer Directions (Brand)

Feverall Directions (Brand)

How should I use Feverall?

This medicine is for rectal use only. Do not take by mouth. Wash your hands before and after use. Take off the foil wrapping. Wet the tip of the suppository with cold tap water to make it easier to use. Lie on your side with your lower leg straightened out and your upper leg bent forward toward your stomach. Lift upper buttock to expose the rectal area. Apply gentle pressure to insert the suppository completely into the rectum, pointed end first. Hold buttocks together for a few seconds. Remain lying down for about 15 minutes to avoid having the suppository come out. Do not use more often than directed.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 3 months of age for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of Feverall contact a poison control center or emergency room at once. NOTE: Feverall is only for you. Do not share Feverall with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Pain Reliever (acetaminophen) Directions (Brand)

Children's Acetaminophen Directions (Brand)

Athenol Directions (Brand)

Arthritis Pain Relief (acetam) Directions (Brand)

acetaminophen Side Effects (Generic)

Acetaminophen Side Effects

Acetaminophen is generally well tolerated and does not cause many side effects. However, in a small number of people, acetaminophen can cause serious side effects that require emergency medical attention. Stop taking acetaminophen and contact your doctor right away or seek emergency medical help if you experience any of the following signs or symptoms:

Hives, itching, or a red, peeling, or blistering skin rash
Swelling of the face, throat, tongue, lips, eyes, hands, lower legs, ankles, or feet
Difficulty breathing or swallowing
Hoarseness

The above list may not include all the potential side effects of acetaminophen. Contact your healthcare professionals if your side effects are unusual or severe or if they do not get better over time. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.

Acetaminophen Overdose: In case of an accidental or intentional overdose of acetaminophen, call your doctor immediately. You can also call the local poison control center or national poison control center at 1-800-222-1222. Overdose symptoms may include nausea, vomiting, loss of appetite, sweating, flu-like symptoms, extreme tiredness, right upper abdominal pain, yellowing of the skin or eyes, and unusual bruising or bleeding.

Source: FDA

Tylenol Side Effects (Brand)

Source: FDA

Infants' Pain and Fever Side Effects (Brand)

Source: FDA

Children's Pain-Fever Relief Side Effects (Brand)

Source: FDA

Mapap Arthritis Pain Side Effects (Brand)

What side effects may I notice from receiving Acetaminophen?

Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-fever or sore throat
-redness, blistering, peeling or loosening of the skin, including inside the mouth
-trouble passing urine or change in the amount of urine
-unusual bleeding or bruising
-unusually weak or tired
-yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-headache
-nausea, vomiting

This list may not describe all possible side effects for Acetaminophen. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA

8HR Muscle Aches-Pain Side Effects (Brand)

Source: FDA

Tylenol 8 Hour Side Effects (Brand)

Source: FDA

Infants' Pain Relief Side Effects (Brand)

Source: FDA

Pain Relief ES (acetaminophen) Side Effects (Brand)

Source: FDA

Tylenol Extra Strength Side Effects (Brand)

What side effects may I notice from receiving Tylenol Extra Strength?

This list may not describe all possible side effects for Tylenol Extra Strength. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA

MAXrelief junior Side Effects (Brand)

Source: FDA

Acetaminophen Pain Relief Side Effects (Brand)

Source: FDA

Pharbetol Side Effects (Brand)

What side effects may I notice from receiving Acetaminophen?

This list may not describe all possible side effects for Acetaminophen. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA

Children's Non-Aspirin Side Effects (Brand)

Source: FDA

Aphen Side Effects (Brand)

Source: FDA

Infant Pain Reliever Side Effects (Brand)

Source: FDA

Infant's Pain Relief Side Effects (Brand)

Source: FDA

Non-Aspirin Side Effects (Brand)

Source: FDA

M-PAP Side Effects (Brand)

What side effects may I notice from receiving Acetaminophen?

Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-redness, blistering, peeling or loosening of the skin, including inside the mouth
-sore throat with fever, headache, rash, nausea, or vomiting
-trouble passing urine or change in the amount of urine
-unusual bleeding or bruising
-unusually weak or tired
-yellowing of the eyes, skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-headache
-nausea, stomach upset

This list may not describe all possible side effects for Acetaminophen. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA

Ed-APAP Side Effects (Brand)

What side effects may I notice from receiving Acetaminophen?

Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-redness, blistering, peeling or loosening of the skin, including inside the mouth
-sore throat with fever, headache, rash, nausea, or vomiting
-trouble passing urine or change in the amount of urine
-unusual bleeding or bruising
-unusually weak or tired
-yellowing of the eyes, skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-headache
-nausea, stomach upset

This list may not describe all possible side effects for Acetaminophen. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA

Children's Pain Reliever Side Effects (Brand)

Source: FDA

Ofirmev Side Effects (Brand)

Source: FDA

Little Remedies Fever and Pain Side Effects (Brand)

Source: FDA

Child Fever Reducer-Pain Relvr Side Effects (Brand)

Source: FDA

Pain Reliever ES(acetaminophn) Side Effects (Brand)

Source: FDA

Children's Fever Reducing Side Effects (Brand)

Source: FDA

Acetaminophen Extra Strength Side Effects (Brand)

Source: FDA

Arthritis Pain Reliever Side Effects (Brand)

Source: FDA

Children's Aurophen Pain-Fever Side Effects (Brand)

What side effects may I notice from receiving Acetaminophen?

This list may not describe all possible side effects for Acetaminophen. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA

Aminofen Side Effects (Brand)

Source: FDA

Shake That Ache Side Effects (Brand)

Source: FDA

Non-Aspirin Extra Strength Side Effects (Brand)

Source: FDA

Tylenol Arthritis Pain Side Effects (Brand)

What side effects may I notice from receiving Tylenol Arthritis Pain?

This list may not describe all possible side effects for Tylenol Arthritis Pain. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA

Infant Fever Reducer-Pain Relf Side Effects (Brand)

Source: FDA

Silapap Side Effects (Brand)

What side effects may I notice from receiving Acetaminophen?

Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-redness, blistering, peeling or loosening of the skin, including inside the mouth
-sore throat with fever, headache, rash, nausea, or vomiting
-trouble passing urine or change in the amount of urine
-unusual bleeding or bruising
-unusually weak or tired
-yellowing of the eyes, skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-headache
-nausea, stomach upset

This list may not describe all possible side effects for Acetaminophen. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA

Mapap (acetaminophen) Side Effects (Brand)

Source: FDA

BetaTemp Side Effects (Brand)

Source: FDA

Children's Tylenol Side Effects (Brand)

Source: FDA

Pain Relief Adult Side Effects (Brand)

Source: FDA

Infant's Acetaminophen Side Effects (Brand)

What side effects may I notice from receiving Acetaminophen?

This list may not describe all possible side effects for Acetaminophen. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA

KinderMed Kids Pain-Fever Side Effects (Brand)

Source: FDA

8 Hour Pain Reliever Side Effects (Brand)

Source: FDA

Non-Aspirin Pain Relief Side Effects (Brand)

Source: FDA

Children's Mapap Side Effects (Brand)

What side effects may I notice from receiving Acetaminophen?

Side effects that you should report to your doctor or health care professional as soon as possible:
-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-redness, blistering, peeling or loosening of the skin, including inside the mouth
-sore throat with fever, headache, rash, nausea, or vomiting
-trouble passing urine or change in the amount of urine
-unusual bleeding or bruising
-unusually weak or tired
-yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
-headache
-nausea, stomach upset

This list may not describe all possible side effects for Acetaminophen. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA

KinderMed Infants Pain-Fever Side Effects (Brand)

Source: FDA

Children's Pain Relief Side Effects (Brand)

Source: FDA

Pain Relief (acetaminophen) Side Effects (Brand)

Source: FDA

Child Pain Rel-Fever Reducer Side Effects (Brand)

Source: FDA

PediaCare Fever Reducer Side Effects (Brand)

Source: FDA

Feverall Side Effects (Brand)

What side effects may I notice from receiving Feverall?

This list may not describe all possible side effects for Feverall. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA

Pain Reliever (acetaminophen) Side Effects (Brand)

Source: FDA

Children's Acetaminophen Side Effects (Brand)

Source: FDA

Athenol Side Effects (Brand)

Source: FDA

Arthritis Pain Relief (acetam) Side Effects (Brand)

Source: FDA

acetaminophen Warnings (Generic)

Acetaminophen Risks, Warnings, and Complications

Acetaminophen can cause serious medical problems in certain people. Talk to your doctor or pharmacist about other options to treat moderate pain if you are at high risk of complications from acetaminophen use. Some of the risks of acetaminophen use include:

ACUTE LIVER FAILURE: Taking too much acetaminophen can lead to acetaminophen poisoning with permanent and severe liver damage that can be life-threatening. Signs of liver damage may include dark-colored urine, extreme tiredness, stomach pain, and yellowing of the skin or eyes. Call your healthcare provider right away if you develop these signs and symptoms while taking acetaminophen. The risk of severe liver damage is higher in people who have a history of liver disease, those who drink more than 3 alcoholic beverages per day, and those who take multiple products containing acetaminophen and exceed the maximum daily dose.
ACETAMINOPHEN OVERDOSE: Many non-prescription and prescription medications contain acetaminophen (for example, Excedrin, Tylenol PM, and Dayquil). Make sure you do not exceed the maximum daily dose (3,000 mg to 4,000 mg) combined from all sources that contain acetaminophen. If you are taking multiple products, keep track of your total daily dose to avoid overdosing. If you notice any overdose symptoms, seek emergency medical help.
ALLERGIC REACTIONS: In a small number of people, acetaminophen can cause a serious allergic reaction. Stop taking acetaminophen and get emergency medical help if you develop a peeling or blistering skin rash, hives, or itching after taking acetaminophen.

Precautions Before Starting Acetaminophen

Tell your doctor if you have ever developed a skin rash after taking acetaminophen. Also, tell your doctor if you have an allergy to any of the active or inactive ingredients in acetaminophen tablets or an allergy to any other drugs. Your pharmacy can give you a list of ingredients.

Give your doctor a complete medical history. Acetaminophen may not be right for people with certain medical conditions such as liver disease or alcoholism.

Give your doctor and pharmacist a complete list of your medications, including prescription drugs, over-the-counter medicines, vitamins, supplements, and herbal products. This can help avoid possible drug interactions.

Do not take over-the-counter acetaminophen if you drink three or more alcoholic beverages per day. Talk to your doctor or pharmacist about the safety of drinking alcohol while taking acetaminophen.

Tell your doctor if you are pregnant, could be pregnant, are planning a pregnancy, or are breastfeeding.

People with a condition called phenylketonuria should talk to their doctor about which acetaminophen products are safe for them to use. In this condition, high serum levels of an amino acid called phenylalanine can cause serious problems. Some brands of nonprescription (OTC) acetaminophen products like chewable tablets may contain aspartame which gets broken down into phenylalanine. Regular acetaminophen tablets and liquid medicine don't contain phenylalanine. If you have phenylketonuria, talk to your healthcare provider about what acetaminophen products are safe for you.

Precautions During Use of Acetaminophen

Call your doctor if your pain lasts more than 10 days, your fever gets worse or lasts more than 3 days, or you develop other new symptoms like skin redness after taking acetaminophen.

Do not take a chronic high dose of acetaminophen regularly without talking to a healthcare provider. If you have severe pain, consult a doctor for appropriate pain management options.

Acetaminophen is present along with other medications in many combination products, some of which are available by prescription and some without a prescription. If your doctor has prescribed acetaminophen, do not take other non-prescription pain medications that also contain acetaminophen. Check the label of all over-the-counter medicines, especially those used to treat cough or cold symptoms, as they may contain acetaminophen. Avoid using two or more products at the same time because they may contain the same active ingredient and could lead to an acetaminophen overdose. This is especially true for children younger than 2 years of age.

When giving non-prescription acetaminophen products to children, read the package label to ensure you are using an acetaminophen product that is suitable for children.

Tell your doctor if you become pregnant while taking acetaminophen.

Tell all your doctors you are on acetaminophen before any surgery, including dental procedures.

Acetaminophen Drug Interactions

Certain other drugs can affect how acetaminophen works. Possible interactions between acetaminophen and other medicines can increase the risk of severe adverse effects. Your doctor may change the dose of your medications or monitor you carefully for side effects if there are known interactions between acetaminophen and your other medicines. The following medications can have possible interactions with acetaminophen:

Blood thinners (anticoagulants) like warfarin (Coumadin)
Medications used to relieve pain, fever, coughs, and colds
Certain medications used to treat seizures, such as phenobarbital, phenytoin (Dilantin), and carbamazepine (Tegretol)
Tuberculosis medications like isoniazid (INH)
Phenothiazines (medications used to treat mental illness and nausea)

The above list may not include all the possible interactions of acetaminophen. Give your doctor or pharmacist a complete list of your medications, including prescription drugs, over-the-counter medicines, dietary supplements, and herbal remedies. Also, tell your healthcare professional if you smoke, drink alcohol, or use recreational drugs because some of these substances can cause serious health complications when used with prescription and over-the-counter medicines.

Tylenol Warnings (Brand)

Infants' Pain and Fever Warnings (Brand)

Children's Pain-Fever Relief Warnings (Brand)

Mapap Arthritis Pain Warnings (Brand)

What may interact with Acetaminophen?

-alcohol
-imatinib
-isoniazid
-other medicines with acetaminophen

What should I tell my health care provider before I take Acetaminophen?

They need to know if you have any of these conditions:

-if you often drink alcohol
-liver disease
-an unusual or allergic reaction to acetaminophen, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using Acetaminophen?

Tell your doctor or health care professional if the pain lasts more than 10 days (5 days for children), if it gets worse, or if there is a new or different kind of pain. Also, check with your doctor if a fever lasts for more than 3 days.

Do not take other medicines that contain acetaminophen with this medicine. Always read labels carefully. If you have questions, ask your doctor or pharmacist.

If you take too much acetaminophen get medical help right away. Too much acetaminophen can be very dangerous and cause liver damage. Even if you do not have symptoms, it is important to get help right away.

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture and heat. Throw away any unused medicine after the expiration date.

8HR Muscle Aches-Pain Warnings (Brand)

Tylenol 8 Hour Warnings (Brand)

Infants' Pain Relief Warnings (Brand)

Pain Relief ES (acetaminophen) Warnings (Brand)

Tylenol Extra Strength Warnings (Brand)

What may interact with Tylenol Extra Strength?

-alcohol
-imatinib
-isoniazid
-other medicines with acetaminophen

What should I tell my health care provider before I take Tylenol Extra Strength?

What should I watch for while using Tylenol Extra Strength?

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture and heat. Throw away any unused medicine after the expiration date.

MAXrelief junior Warnings (Brand)

Acetaminophen Pain Relief Warnings (Brand)

Pharbetol Warnings (Brand)

What may interact with Acetaminophen?

-alcohol
-imatinib
-isoniazid
-other medicines with acetaminophen

What should I tell my health care provider before I take Acetaminophen?

What should I watch for while using Acetaminophen?

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture and heat. Throw away any unused medicine after the expiration date.

Children's Non-Aspirin Warnings (Brand)

Aphen Warnings (Brand)

Infant Pain Reliever Warnings (Brand)

Infant's Pain Relief Warnings (Brand)

Non-Aspirin Warnings (Brand)

M-PAP Warnings (Brand)

What may interact with Acetaminophen?

-alcohol
-imatinib
-isoniazid
-other medicines that contain acetaminophen

What should I tell my health care provider before I take Acetaminophen?

They need to know if you have any of these conditions:

-if you often drink alcohol
-liver disease
-phenylketonuria
-an unusual or allergic reaction to acetaminophen, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using Acetaminophen?

Tell your doctor or health care professional if the pain lasts more than 10 days (5 days for children), if it gets worse, or if there is a new or different kind of pain. Also, check with your doctor if a fever lasts for more than 3 days.

Do not take acetaminophen (Tylenol) or other medicines that contain acetaminophen with this medicine. Too much acetaminophen can be very dangerous and cause an overdose. Always read labels carefully.

Report any possible overdose to your doctor right away, even if there are no symptoms. The effects of extra doses may not be seen for many days.

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture and heat. Throw away any unused medicine after the expiration date.

Ed-APAP Warnings (Brand)

What may interact with Acetaminophen?

-alcohol
-imatinib
-isoniazid
-other medicines that contain acetaminophen

What should I tell my health care provider before I take Acetaminophen?

What should I watch for while using Acetaminophen?

Tell your doctor or health care professional if the pain lasts more than 10 days (5 days for children), if it gets worse, or if there is a new or different kind of pain. Also, check with your doctor if a fever lasts for more than 3 days.

Do not take acetaminophen (Tylenol) or other medicines that contain acetaminophen with this medicine. Too much acetaminophen can be very dangerous and cause an overdose. Always read labels carefully.

Report any possible overdose to your doctor right away, even if there are no symptoms. The effects of extra doses may not be seen for many days.

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture and heat. Throw away any unused medicine after the expiration date.

Children's Pain Reliever Warnings (Brand)

Ofirmev Warnings (Brand)

Little Remedies Fever and Pain Warnings (Brand)

Child Fever Reducer-Pain Relvr Warnings (Brand)

Pain Reliever ES(acetaminophn) Warnings (Brand)

Children's Fever Reducing Warnings (Brand)

Acetaminophen Extra Strength Warnings (Brand)

Arthritis Pain Reliever Warnings (Brand)

Children's Aurophen Pain-Fever Warnings (Brand)

What may interact with Acetaminophen?

-alcohol
-imatinib
-isoniazid
-other medicines with acetaminophen

What should I tell my health care provider before I take Acetaminophen?

What should I watch for while using Acetaminophen?

Tell your doctor or health care professional if the pain lasts more than 10 days (5 days for children), if it gets worse, or if there is a new or different kind of pain. Also, check with your doctor if a fever lasts for more than 3 days.

Do not take acetaminophen (Tylenol) or other medicines that contain acetaminophen with this medicine. Too much acetaminophen can be very dangerous and cause an overdose. Always read labels carefully.

Report any possible overdose to your doctor right away, even if there are no symptoms. The effects of extra doses may not be seen for many days.

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture and heat. Throw away any unused medicine after the expiration date.

Aminofen Warnings (Brand)

Shake That Ache Warnings (Brand)

Non-Aspirin Extra Strength Warnings (Brand)

Tylenol Arthritis Pain Warnings (Brand)

What may interact with Tylenol Arthritis Pain?

-alcohol
-imatinib
-isoniazid
-other medicines with acetaminophen

What should I tell my health care provider before I take Tylenol Arthritis Pain?

What should I watch for while using Tylenol Arthritis Pain?

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture and heat. Throw away any unused medicine after the expiration date.

Infant Fever Reducer-Pain Relf Warnings (Brand)

Silapap Warnings (Brand)

What may interact with Acetaminophen?

-alcohol
-imatinib
-isoniazid
-other medicines that contain acetaminophen

What should I tell my health care provider before I take Acetaminophen?

What should I watch for while using Acetaminophen?

Tell your doctor or health care professional if the pain lasts more than 10 days (5 days for children), if it gets worse, or if there is a new or different kind of pain. Also, check with your doctor if a fever lasts for more than 3 days.

Do not take acetaminophen (Tylenol) or other medicines that contain acetaminophen with this medicine. Too much acetaminophen can be very dangerous and cause an overdose. Always read labels carefully.

Report any possible overdose to your doctor right away, even if there are no symptoms. The effects of extra doses may not be seen for many days.

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture and heat. Throw away any unused medicine after the expiration date.

Mapap (acetaminophen) Warnings (Brand)

BetaTemp Warnings (Brand)

Children's Tylenol Warnings (Brand)

Pain Relief Adult Warnings (Brand)

Infant's Acetaminophen Warnings (Brand)

What may interact with Acetaminophen?

-alcohol
-imatinib
-isoniazid
-other medicines with acetaminophen

What should I tell my health care provider before I take Acetaminophen?

What should I watch for while using Acetaminophen?

Tell your doctor or health care professional if the pain lasts more than 10 days (5 days for children), if it gets worse, or if there is a new or different kind of pain. Also, check with your doctor if a fever lasts for more than 3 days.

Do not take acetaminophen (Tylenol) or other medicines that contain acetaminophen with this medicine. Too much acetaminophen can be very dangerous and cause an overdose. Always read labels carefully.

Report any possible overdose to your doctor right away, even if there are no symptoms. The effects of extra doses may not be seen for many days.

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture and heat. Throw away any unused medicine after the expiration date.

KinderMed Kids Pain-Fever Warnings (Brand)

8 Hour Pain Reliever Warnings (Brand)

Non-Aspirin Pain Relief Warnings (Brand)

Children's Mapap Warnings (Brand)

What may interact with Acetaminophen?

-alcohol
-imatinib
-isoniazid
-other medicines with acetaminophen

What should I tell my health care provider before I take Acetaminophen?

What should I watch for while using Acetaminophen?

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture and heat. Throw away any unused medicine after the expiration date.

KinderMed Infants Pain-Fever Warnings (Brand)

Children's Pain Relief Warnings (Brand)

Pain Relief (acetaminophen) Warnings (Brand)

Child Pain Rel-Fever Reducer Warnings (Brand)

PediaCare Fever Reducer Warnings (Brand)

Feverall Warnings (Brand)

What may interact with Feverall?

-alcohol
-imatinib
-isoniazid
-other medicines with acetaminophen

What should I tell my health care provider before I take Feverall?

What should I watch for while using Feverall?

Tell your doctor or health care professional if the pain lasts more than 10 days (5 days for children), if it gets worse, or if there is a new or different kind of pain. Also, check with your doctor if a fever lasts for more than 3 days.

Do not take acetaminophen (Tylenol) or other medicines that contain acetaminophen with this medicine. Too much acetaminophen can be very dangerous and cause an overdose. Always read labels carefully.

Report any possible overdose to your doctor right away, even if there are no symptoms. The effects of extra doses may not be seen for many days.

Where should I keep my medicine?

Keep out of reach of children.

Store at room temperature below 27 degrees C (80 degrees F). Protect from moisture and heat. Throw away any unused medicine after the expiration date.

Pain Reliever (acetaminophen) Warnings (Brand)

Children's Acetaminophen Warnings (Brand)

Athenol Warnings (Brand)

Arthritis Pain Relief (acetam) Warnings (Brand)

acetaminophen Pros & Cons (Generic)

Acetaminophen Pros and Cons

pros header.svg

Acetaminophen is effective in reducing fever and relieving minor aches and pains.
Taking acetaminophen is associated with minor risks for most people.
This medicine is available in various forms like regular tablets, extended-release and chewable tablets, liquid, powder, and suppositories.
It is available in a low-cost generic version.
Acetaminophen is safe for use by children.
Acetaminophen is less likely to cause upset stomach, stomach bleeding, ulcers, bruising, and bleeding compared to ibuprofen and aspirin.
Compared to ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen is a better option for people with severe renal impairment or kidney disease.

cons header.svg

Acetaminophen can treat minor pain and reduce fever, but it does not lessen swelling and inflammation.
It may not work well for moderate to severe pain.
Acetaminophen may not be safe for people with hepatic impairment (reduced liver function) or heavy alcohol use.
Many non-prescription pain relief combination medications contain acetaminophen, and you need to be careful not to overdose.

acetaminophen Pharmacist Tips (Generic)

Acetaminophen Tips from Pharmacists

Make sure you do not take more than 3,000 to 4,000 mg of acetaminophen in one day from all products combined.
The orally disintegrating tablet or powder form of acetaminophen can be placed directly on the tongue. It will dissolve almost immediately, and you can then swallow the medicine.
If you are giving liquid acetaminophen to a child for pain relief or fever, use dosing devices like a syringe or cup to measure the dose accurately. Using a household spoon can result in the wrong dose.
Store acetaminophen suppositories in a cool, dry place to prevent them from melting. Open the foil wrapper of the suppository only when you are ready to use it.
Contact your healthcare provider if your pain is no better after 10 days or your fever is still present after 3 days of taking acetaminophen.
Do not take acetaminophen if you are a heavy drinker (3 or more alcoholic beverages per day).

acetaminophen Rx Savings Tips (Generic)

Acetaminophen Rx Savings Tips

Acetaminophen is a generic medication, and it is available at significantly lower prices than the brand-name drugs. Brand names Mapap Arthritis Pain, Tylenol, and others and generic acetaminophen contain the same medicine and are equally effective and safe. Like with most medications, the generic drug offers better value. A BuzzRx acetaminophen coupon can result in big savings on the brand name and generic forms of the drug. With a BuzzRx discount card, savings card, or discount coupons, the medication could cost you a fraction of retail prices. Acetaminophen may be under $7 for 90 tablets of the 650 mg dose at Walmart, Walgreens, Rite Aid, CVS Pharmacy, and other participating pharmacies with a BuzzRx discount card or free coupon. For the biggest discounts on acetaminophen, give the checkout clerk your BuzzRx acetaminophen discount coupon when you purchase acetaminophen over-the-counter.

Lowest Price for Acetaminophen

Brand
$15.79

Generic
$6.26

VIEW DISCOUNTS
Pricing based on most commonly-filled versions. Select the strength and quantity of your medication for the most accurate pricing.

acetaminophen Common Questions (Generic)

Common Questions about Acetaminophen

Are acetaminophen and ibuprofen the same?

Acetaminophen and ibuprofen are not the same. However, there are some similarities between the two. Both are used to treat pain and fever and are available without a prescription. The difference between them is that ibuprofen (Advil, Motrin) is a nonsteroidal anti-inflammatory drug (NSAID) and is more effective in reducing swelling and inflammation compared to acetaminophen (Mapap Arthritis Pain, Tylenol). Also, acetaminophen can be hard on the liver, while ibuprofen can be hard on the kidneys.

Is paracetamol the same as acetaminophen?

Yes, paracetamol and acetaminophen are the same things. Acetaminophen is the name used in the United States. Paracetamol is the official proprietary name of the medicine and is used everywhere else in the world.

What is stronger, acetaminophen or ibuprofen?

Acetaminophen helps with fever and pain, while ibuprofen helps with fever, pain, swelling, and inflammation. Ibuprofen may be more effective for certain types of pain.

How quickly does acetaminophen work?

Acetaminophen works quickly, usually within 30 minutes. This medicine reaches peak plasma concentration around 90 minutes after you take a dose.

Does acetaminophen help you sleep?

Acetaminophen does not directly help you sleep. However, it can help to reduce minor aches and pains which may be keeping you up at night, and in this way, it can indirectly improve your sleep. A combination medicine called Tylenol PM contains acetaminophen and diphenhydramine, and this product can help you sleep.

Is it safe to take acetaminophen every day?

Acetaminophen is meant to be used on a short-term basis to treat fever and pain. Taking this medication every day for the long term can cause liver damage. You should talk to your doctor if your pain is no better after 10 days or your fever does not go away after 3 days of taking acetaminophen.

What is the price of acetaminophen without insurance?

Without insurance, acetaminophen can be as high as $20.77, but with a free BuzzRx prescription discount coupon, you could pay as low as $6.26 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.

What is the price of acetaminophen with insurance?

Ask your pharmacist or insurance provider for your copay price on acetaminophen—copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for acetaminophen. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.

Find the best discount on Acetaminophen »