What side effects may I notice from receiving Alogliptin, Pioglitazone?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-blood in the urine
-bone fractures
-breathing problems
-changes in vision
-joint pain
-redness, blistering, peeling or loosening of the skin, including inside the mouth
-signs and symptoms of heart failure like breathing problems, fast, irregular heartbeat, sudden weight gain; swelling of the ankles, feet, hands; unusually weak or tired
-signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
-signs and symptoms of low blood sugar such as feeling anxious, confusion, dizziness, increased hunger, unusually weak or tired, sweating, shakiness, cold, irritable, headache, blurred vision, fast heartbeat, loss of consciousness
-signs and symptoms of muscle injury like dark urine; trouble passing urine or change in the amount of urine; unusually weak or tired; muscle pain; back pain

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-headache
-mild muscle pain
-stuffy or runny nose
-sore throat

This list may not describe all possible side effects for Alogliptin, Pioglitazone. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.