Warnings


What may interact with Alunbrig?

This medicine may interact with the following medications:

-antiviral medicines for HIV or AIDS
-boceprevir
-certain medicines for fungal infections like ketoconazole, itraconazole, posaconazole, and voriconazole
-certain medicines for seizures like carbamazepine, phenobarbital, phenytoin
-clarithromycin
-conivaptan
-female hormones, like estrogens or progestins and birth control pills, patches, rings, or injections
-grapefruit juice
-rifampin
-St. John''s Wort

What should I tell my health care provider before I take Alunbrig?

They need to know if you have any of these conditions:

-diabetes
-eye disease, vision problems
-high blood pressure
-history of irregular heartbeat
-history of pancreatitis
-kidney disease
-liver disease
-lung or breathing disease, like asthma
-muscle aches or weakness
-scarring or thickening of the lungs
-an unusual or allergic reaction to brigatinib, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using Alunbrig?

Tell your doctor or health care professional right away if you have any change in your eyesight.

You may need blood work done while you are taking this medicine.

Do not become pregnant while taking this medicine or for 4 months after the last dose. Men should use effective contraception during treatment and for 3 months after the last dose. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for 1 week after the last dose.

Birth control pills may not work properly while you are taking this medicine. Talk to your doctor about using an extra method of birth control.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body''s ability to fight infections. Try to avoid being around people who are sick.

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

Where should I keep my medicine?

Keep out of the reach of children.

Store at controlled room temperature between 20 and 25 degrees C (68 and 67 degrees F). Throw away any unused medicine after the expiration date.