Amlodipine Besylate-Benazepril
Medically Reviewed by Dr. Harshi Dhingra, M.D.
Last Reviewed: Mar 28, 2023
Pros & Cons
Amlodipine-Benazepril (Lotrel) Pros and Cons
- Both amlodipine and benazepril are first choice medications for the treatment of hypertension.
- This combination works well in people who have not responded to monotherapy (either medication alone).
- It is convenient to take amlodipine-benazepril combination because you need to take fewer pills.
- Amlodipine-benazepril is available in a low-cost generic version.
- Amlodipine-benazepril is prescribed only after you have tried and failed to respond to at least one of these medications alone.
- The combination of amlodipine-benazepril comes in fixed doses, so dose adjustments are more challenging if one medication is not working as well as the other.
- Amlodipine-benazepril is not safe for use during pregnancy and can cause birth defects, especially if used during the second or third trimester.
- Benazepril can cause ACE inhibitor induced cough and throat irritation in some people.
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