Do not take this medicine with any of the following medications:

-amprenavir, fosamprenavir
-aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone
-atazanavir; cobicistat
-bosentan
-metyrapone


This medicine may also interact with the following medications:

-acetaminophen
-antiviral medicines for HIV or AIDS
-aprepitant
-barbiturates
-certain antibiotics like clarithromycin, erythromycin, rifampin, rifabutin, rifapentine, and possibly penicillins or tetracyclines
-certain diuretics like amiloride, spironolactone, triamterene
-certain medicines for fungal infections like griseofulvin, ketoconazole, itraconazole
-certain medications for high blood pressure or heart conditions like ACE-inhibitors, Angiotensin-II receptor blockers, eplerenone
-certain medicines for seizures like carbamazepine, oxcarbazepine, phenobarbital, phenytoin
-cholestyramine
-cobicistat
-corticosteroid like hydrocortisone and prednisolone
-cyclosporine
-dantrolene
-felbamate
-grapefruit juice
-heparin
-lamotrigine
-medicines for diabetes, including pioglitazone
-modafinil
-NSAIDs
-potassium supplements
-pyrimethamine
-raloxifene
-St. John''s wort
-sulfasalazine
-tamoxifen
-topiramate
-thyroid hormones
-warfarin

They need to know if you have any of these conditions:
-blood vessel disease or blood clots
-breast, cervical, endometrial, or uterine cancer
-diabetes
-endometriosis
-fibroids
-gallbladder disease
-heart disease or recent heart attack
-high blood cholesterol
-high blood pressure
-high level of calcium in the blood
-hysterectomy
-kidney disease
-liver disease
-mental depression
-migraine headaches
-porphyria
-stroke
-systemic lupus erythematosus (SLE)
-tobacco smoker
-vaginal bleeding
-an unusual or allergic reaction to estrogens, progestins, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your health care professional for regular checks on your progress. You should have a complete check-up every 6 months. You will need a regular breast and pelvic exam. You should also discuss the need for regular mammograms with your health care professional, and follow his or her guidelines.

This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.

If you have any reason to think you are pregnant; stop taking this medicine at once and contact your doctor or health care professional.

Tobacco smoking increases the risk of getting a blood clot or having a stroke, especially if you are more than 35 years old. You are strongly advised not to smoke.

If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.

If you are going to have elective surgery, you may need to stop taking this medicine beforehand. Consult your health care professional for advice prior to scheduling the surgery.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.