Do not take this medicine with any of the following medications:

-cisapride
-dofetilide
-dronedarone
-MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
-pimozide
-thioridazine
-ziprasidone

This medicine may also interact with the following medications:

-antihistamines for allergy
-antiviral medicines for HIV or AIDS
-atropine
-beta-blockers like metoprolol and propranolol
-certain medicines for bladder problems like oxybutynin, tolterodine
-certain medicines for depression, anxiety, or psychotic disturbances
-certain medicines for Parkinson''s disease like benztropine, trihexyphenidyl
-certain medicines for stomach problems like dicyclomine, hyoscyamine
-certain medicines for travel sickness like scopolamine
-diuretics
-ipratropium
-medicines for colds
-medicines for fungal infections like ketoconazole and itraconazole
-other medicines for breathing problems
-other medicines that prolong the QT interval (cause an abnormal heart rhythm)
-tiotropium

They need to know if you have any of these conditions:

-bladder problems or difficulty passing urine
-diabetes
-glaucoma
-heart disease or irregular heartbeat
-high blood pressure
-kidney disease
-pheochromocytoma
-prostate disease
-seizures
-thyroid disease
-an unusual or allergic reaction to umeclidinium, vilanterol, lactose, milk proteins, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor or health care professional for regular checkups. Tell your doctor or health care professional if your symptoms do not get better.

If your symptoms get worse or if you need your short-acting inhalers more often, call your doctor right away. Do not use this medicine more than once every 24 hours.

Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Store in a dry place away from direct heat or sunlight. Throw away 6 weeks after you remove the inhaler from the foil tray, or after the dose indicator reads 0, whichever comes first. Throw away any unopened packages after the expiration date.