Do not take this medicine with any of the following medications:
-if you have taken a Monoamine Oxidase (MAO) inhibitor like Carbex, Eldepryl, Marplan, Nardil, and Parnate within the past 14 days

This medicine may also interact with the following medications:
-alcohol
-barbiturate medicines for inducing sleep or treating seizures
-beta blockers
-certain narcotic pain medicines like codeine or morphine
-heart medicines such as digoxin
-medicines for colds and breathing difficulties
-medicines for high blood pressure
-medicines for mental depression

They need to know if you have any of these conditions:
-eye abrasion, inflammation, or infection
-depression
-heart disease or high blood pressure
-kidney or liver disease
-Raynaud''s disease
-wear contact lenses
-an unusual or allergic reaction to apraclonidine, clonidine or other medications, foods, dyes or preservatives
-pregnant or trying to become pregnant
-breast-feeding

Visit your doctor or health care professional for regular checks on your progress. Report any serious side effects right away. Stop using this medicine if your eyes get swollen, painful, or have a discharge, and see your doctor or health care professional as soon as you can.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this drug affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol can make you more drowsy and dizzy. Avoid alcoholic drinks.

If you wear contact lenses, take them out before putting drops in the eye. Contact lenses may be put back in 15 minutes after putting the drops in your eyes.

Wear dark glasses if this medicine makes your eyes more sensitive to light.

Keep out of the reach of children.

Store this medicine in the original bottle between 2 and 27 degrees C (36 to 80 degrees F). Protect from freezing and light. Throw away any unused medication after the expiration date.