Boostrix Risks, Warnings, and Complications

FAINTING: Some people can faint after receiving injectable vaccines like the Tdap (Boostrix) vaccine. The risk is higher in people who have fainted after receiving other injectable vaccines before, such as the influenza virus vaccine. Tell your doctor if this is the case so that they can monitor you. Signs and symptoms of impending fainting may include a burning sensation, changes in vision, and twitching or stiffening of the limbs. 

SEVERE ALLERGIC REACTIONS: As with any vaccine, there is a (rare) risk of a severe allergic reaction to Tdap (Boostrix) vaccine. People who have a latex allergy should let their doctor know before receiving Boostrix because the tip cap of this vaccine contains latex. (Adacel brand does not contain latex). 

Tell your doctor if you have had an allergic reaction called an arthus reaction to a tetanus toxoid-containing vaccine in the past. Signs and symptoms of an arthus reaction include pain, swelling, and hardening at the injection site. In this case, your doctor will tell you to wait at least 10 years before getting another dose of a tetanus immune globulin vaccine like Tdap.

Your healthcare provider might ask you to remain in the clinic or pharmacy for a short time to make sure you have access to medical care in case of a serious allergic reaction. However, in addition to immediate allergic reactions, sometimes acute allergic reactions can occur later on (after you’ve left the doctor’s office or pharmacy). 

Seek immediate medical help if you experience signs and symptoms such as feeling faint, closing of the throat, swelling of the throat or face, chest pain, difficulty breathing, skin rash, hives, itching, shaking, dizziness, or nausea.

NERVOUS SYSTEM DISORDERS: Very rarely, a nervous system condition called Guillain-Barre syndrome (GBS) or other nerve problems can develop after receiving Tdap (Boostrix). The risk of this occurring is higher in people over 50 years of age. Tell your doctor if you have a history of GBS within 6 weeks of receiving a tetanus toxoid containing vaccine. Contact your healthcare provider immediately if you experience signs and symptoms of nerve damage such as pain, muscle weakness, or paralysis within 6 weeks of receiving Tdap (Boostrix) vaccine. 

IMMUNE SYSTEM DISORDERS: The Tdap (Boostrix) vaccine may not work properly in people with immune system disorders or weakened immune systems. Such individuals may have a suboptimal immune response to the vaccine and therefore continue to be at high risk of tetanus, diphtheria, and whooping cough even after getting vaccinated. Talk to your provider if you have medical conditions that affect the immune system, such as HIV or cancer, or if you take any medications that can weaken your immune system, such as steroids or transplant medicines.