Warnings


What may interact with BOSULIF?

This medicine may interact with the following:

-amprenavir
-antacids
-aprepitant
-atazanavir
-boceprevir
-certain medications for bacterial infections like ciprofloxacin, clarithromycin, erythromycin, and telithromycin
-certain medications for fungal infections like fluconazole, ketoconazole, itraconazole, posaconazole, and voriconazole
-certain medications for seizures like carbamazepine, phenobarbital, and phenytoin
-certain medications for stomach problems like cimetidine, famotidine, ranitidine, esomeprazole, dexlansoprazole, lansoprazole, omeprazole, pantoprazole, and rabeprazole
-conivaptan
-crizotinib
-darunavir
-diltiazem
-fosamprevir
-grapefruit juice
-imatinib
-indinavir
-nefazodone
-nelfinavir
-rifampin
-ritonavir
-saquinavir
-St. John''s Wort
-telaprevir
-verapamil

What should I tell my health care provider before I take BOSULIF?

They need to know if you have any of these conditions:

-diabetes (high blood sugar)
-heart disease
-high blood pressure
-kidney disease
-liver disease
-an unusual or allergic reaction to bosutinib, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using BOSULIF?

You may need blood work done while you are taking this medicine.

This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body''s ability to fight infections. Try to avoid being around people who are sick.

Do not become pregnant while taking this medicine or for at least 2 weeks after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine or for at least 2 weeks after the last dose.

This medicine may interfere with the ability to have a child. Talk with your doctor or health care professional if you are concerned about your fertility.

Where should I keep my medicine?

Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Get rid of any unused medicine after the expiration date.
To get rid of medicines that are no longer needed or have expired:

-Take the medicine to a medicine take-back program. Check with your pharmacy or law enforcement to find a location.
-If you cannot return the medicine, check the label or package insert to see if the medicine should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your health care provider. If it is safe to put it in the trash, take the medicine out of the container. Mix the medicine with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.