Do not take this medicine with any of the following medications:

-cisapride
-dofetilide
-dronedarone
-MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate
-pimozide
-thioridazine
-ziprasidone

This medicine may also interact with the following medications:

-antiviral medicines for HIV or AIDS
-beta-blockers like metoprolol and propranolol
-certain medicines for depression, anxiety, or psychotic disturbances
-certain medicines for fungal infections like ketoconazole, itraconazole, posaconazole, voriconazole
-conivaptan
-diuretics
-medicines for colds
-nefazodone
-other medicines for breathing problems
-other medicines that prolong the QT interval (cause an abnormal heart rhythm)

They need to know if you have any of these conditions:

-bone problems
-diabetes
-eye disease, vision problems
-immune system problems
-heart disease or irregular heartbeat
-high blood pressure
-infection
-pheochromocytoma
-seizures
-thyroid disease
-an unusual or allergic reaction to fluticasone, vilanterol, milk proteins, corticosteroids, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor or health care professional for regular checkups. Tell your doctor or health care professional if your symptoms do not get better. Do not use this medicine more than once every 24 hours.

NEVER use this medicine for an acute asthma or COPD attack. You should use your short-acting rescue inhalers for this purpose. If your symptoms get worse or if you need your short-acting inhalers more often, call your doctor right away.

If you are going to have surgery tell your doctor or health care professional that you are using this medicine. Try not to come in contact with people with the chicken pox or measles. If you do, call your doctor.

This medicine may increase blood sugar. Ask your healthcare provider if changes in diet or medicines are needed if you have diabetes.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Store in a dry place away from direct heat or sunlight. Throw away 6 weeks after you remove the inhaler from the foil tray, or after the dose indicator reads 0, whichever comes first. Throw away any unopened packages after the expiration date.