Warnings


What may interact with BREZTRI?

Do not take the medicine with any of the following medications:

-cisapride
-dofetilide
-dronedarone
-MAOIs like Marplan, Nardil, and Parnate
-other medicines that contain long-acting beta-2 agonists (LABAs) like arformoterol, formoterol, indacaterol, olodaterol, salmeterol, vilanterol
-pimozide
-procarbazine
-thioridazine

This medicine may also interact with the following medications:

-antihistamines for allergy, cough, and cold
-atropine
-certain antibiotics like clarithromycin, telithromycin
-certain antivirals for HIV or hepatitis
-certain heart medicines like atenolol, metoprolol
-certain medicines for bladder problems like oxybutynin, tolterodine
-certain medicines for blood pressure, heart disease, irregular heartbeat
-certain medicines for depression, anxiety, or psychotic disturbances
-certain medicines for fungal infections like ketoconazole, itraconazole
-certain medicines for Parkinson''s disease like benztropine, trihexyphenidyl
-certain medicines for stomach problems like dicyclomine, hyoscyamine
-certain medicines for travel sickness like scopolamine
-diuretics
-grapefruit juice
-mifepristone
-other inhaled medicines that contain anticholinergics such as aclidinium, ipratropium, tiotropium, umeclidinium
-other medicines that prolong the QT interval (an abnormal heart rhythm)
-some vaccines
-steroid medicines like prednisone or cortisone
-stimulant medicines for attention disorders, weight loss, or to stay awake
-theophylline

What should I tell my health care provider before I take BREZTRI?

They need to know if you have any of these conditions:

-bladder problems or trouble passing urine
-bone problems
-diabetes
-eye disease, vision problems
-heart disease
-high blood pressure
-history of irregular heartbeat
-immune system problems
-infection
-kidney disease
-pheochromocytoma
-prostate disease
-seizures
-thyroid disease
-an unusual or allergic reaction to budesonide, formoterol, glycopyrrolate, medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using BREZTRI?


Visit your health care professional for regular checks on your progress. Tell your health care professional if your symptoms do not start to get better or if they get worse.



NEVER use this medicine for an acute asthma or COPD attack. You should use your short-acting rescue inhalers for this purpose. If your symptoms get worse or if you need your short-acting inhalers more often, call your doctor right away.



This medicine may increase your risk of getting an infection. Tell your doctor or health care professional if you are around anyone with measles or chickenpox, or if you develop sores or blisters that do not heal properly.



Do not get this medicine in your eyes. It can cause irritation, pain, or blurred vision.

Where should I keep my medicine?

Keep out of the reach of children.

Store in a dry place at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from heat. Do not freeze. Do not use or store near heat or flame, as the canister may burst. Throw away the inhaler 3 months after you open the foil pouch (for the 120-inhalation canister), or 3 weeks after you open the foil pouch (for the 28-inhalation canister), or when the dose indicator reaches zero "0", whichever comes first.