Buspirone Uses

Buspirone is used to treat generalized anxiety disorder. It is also used off-label to help with smoking cessation. 

There may be other uses of buspirone—your doctor or pharmacist can give you further drug information.

Buspirone Mechanism of Action

Buspirone changes the amount of certain natural substances in the brain that regulate mood.

Buspirone Doses

Buspirone is available as 5 mg, 7.5 mg, 10 mg, 15 mg, and 30 mg tablets. 

The typical starting dose of buspirone for anxiety disorders is 10-15 mg per day every 8-12 hours in divided doses. The dose can be increased by 5 mg/day at intervals of 2-3 days to a maintenance dose of 15-30 mg per day. The maximum daily dosage is 60 mg/day.

For smoking cessation, the dose of buspirone is 30-60 mg/day starting 2 weeks before quitting smoking and continuing for 9-13 weeks.