Do not take this medicine with any of the following medications:

-dexamethasone (more than 1 dose)
-certain medicines for seizures like carbamazepine, oxcarbazepine, phenobarbital, phenytoin
-rifabutin
-rifampin
-rifapentine
-St. John''s wort; Hypericum perforatum
This medicine may also interact with the following medications:

-certain antibiotics like azithromycin, clarithromycin, erythromycin
-methadone

They need to know if you have any of these conditions:

-heart disease
-liver disease
-mental health disease
-an unusual or allergic reaction to cabotegravir, rilpivirine, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Visit your doctor or health care provider for regular check ups. Discuss any new symptoms with your doctor. You will need to have important blood work done while on this medicine.
HIV is spread to others through sexual or blood contact. Talk to your doctor about how to stop the spread of HIV.
This medicine may cause serious skin reactions. They can happen weeks to months after starting the medicine. Contact your health care provider right away if you notice fevers or flu-like symptoms with a rash. The rash may be red or purple and then turn into blisters or peeling of the skin. Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms.

This medicine is given in a hospital or clinic. It will not be stored at home.