Do not take this medicine with any of the following medications:
-aminocaproic acid
-aprotinin
-tranexamic acid

This medicine may also interact with the following medications:
-antiinflammatory drugs, NSAIDs like ibuprofen
-aspirin and aspirin-like medicines
-blood thinners, like warfarin, heparin or enoxaparin
-dipyridamole

They need to know if you have any of these conditions:
-aneurysm
-bleeding problems or problems with blood clotting
-blood vessel disease or damaged blood vessels
-diabetic retinopathy
-head injury or tumor
-high blood pressure
-infection
-irregular heartbeats
-previous stroke
-recent biopsy or surgery
-an unusual or allergic reaction to alteplase, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Your condition will be monitored carefully while you are receiving this medicine. Follow the advice of your doctor or health care professional exactly. You may need bed rest to minimize the risk of bleeding.

This medicine can make you bleed more easily. This effect can last for several days. Take special care brushing or flossing your teeth.

Do not take aspirin, ibuprofen, or other nonprescription pain relievers during or for several days after alteplase treatment unless otherwise instructed by your doctor or health care professional.

You may feel dizzy or lightheaded. To avoid the risk of dizzy or fainting spells, sit or stand up slowly, especially if you are an older patient.

This does not apply. You will not be given this medicine to store at home.