Chlorthalidone

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jul 26, 2022

Pros & Cons


Chlorthalidone Pros and Cons

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  • Chlorthalidone is effective in helping the kidneys remove excess salt and water in the body. It works especially well to lower blood pressure in Black people and in people who have not responded well to thiazide diuretics.
  • By helping to control high blood pressure, chlorthalidone lowers the risk of heart attacks and stroke.
  • This medication is a good option for people who have both heart failure and high blood pressure.
  • Chlorthalidone can raise serum calcium levels and is a good choice for people with osteoporosis.

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  • Chlorthalidone can make you urinate more than usual.
  • It is not a good choice for people with kidney disease.
  • Chlorthalidone has a higher chance of causing electrolyte imbalance compared to thiazide diuretics.
  • People with a sulfa drug allergy should not take chlorthalidone.
  • Chlorthalidone can lead to an increased risk of gout attacks in people who have gout.