Side Effects


What side effects may I notice from receiving Clozapine?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
-breathing problems
-changes in vision
-confusion
-constipation
-fast, irregular heartbeat
-fever or chills, sore throat
-inability to keep still
-males: prolonged or painful erection
-problems with balance, talking, walking
-rash, fever, and swollen lymph nodes
-redness, blistering, peeling or loosening of the skin, including inside the mouth
-seizures
-shortness of breath, chest pain, swelling in a leg
-signs and symptoms of high blood sugar such as being more thirsty or hungry or having to urinate more than normal. You may also feel very tired or have blurry vision.
-signs and symptoms of liver injury like dark yellow or brown urine; general ill feeling or flu-like symptoms; light-colored stools; loss of appetite; nausea; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin
-signs and symptoms of low blood pressure like dizziness; feeling faint or lightheaded, falls; unusually weak or tired
-signs and symptoms of neuroleptic malignant syndrome like confusion; fast or irregular heartbeat; high fever; increased sweating; stiff muscles
-stomach pain or swelling
-sudden numbness or weakness of the face, arm, or leg
-trouble passing urine
-trouble swallowing
-uncontrollable movements of the arms, face, head, mouth, neck, or upper body
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-drooling
-drowsiness
-dry mouth
-headache
-weight gain

This list may not describe all possible side effects for Clozapine. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Source: FDA