Cymbalta

Medically Reviewed by Harshi Dhingra, M.D.

Last Reviewed: Jun 22, 2022

Common Questions


Common Questions about Cymbalta (duloxetine)


Should I take Cymbalta at night or in the morning?

Most people take Cymbalta in the morning, but you can take it at night. If this medication makes you drowsy during the daytime, it might help to take it at night. You should take your Cymbalta at around the same time every day. 



How long does it take for Cymbalta to work?

Most people notice an improvement in mood or pain symptoms within 1-2 weeks of starting Cymbalta. However, it can take up to 12 weeks to get the full benefits of this medication.



Can Cymbalta keep you awake at night?

Insomnia (trouble falling asleep or staying asleep) is a possible side effect of Cymbalta. This usually improves after the first week or two as you continue taking the medicine.



Is Cymbalta safe for seniors?

Yes, Cymbalta is safe for seniors. However, the doctor may prescribe a lower starting dose in older individuals.



Does Cymbalta help with pain?

Cymbalta can help with pain from diabetic peripheral neuropathy, chronic pain from musculoskeletal conditions, and pain in patients with fibromyalgia. This medication increases the availability of two brain chemicals - serotonin and norepinephrine - which allows the brain to control pain better. 



Can I drink alcohol on Cymbalta?

Drinking alcohol while on Cymbalta is not recommended. This can increase the risk of serious side effects. In addition, alcohol can add to the drowsiness caused by this medicine. 



What is the price of Cymbalta without insurance?

Without insurance, Cymbalta can be as high as $236 (generic), but with a free BuzzRx prescription discount coupon, you could pay as low as $12.29 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not. 



What is the price of Cymbalta with insurance?

Ask your pharmacist or insurance provider for your copay price on Cymbalta—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for Cymbalta. When using the BuzzRx lookup tool to find the price of your medication, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.