Desonide

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Mar 25, 2025

Common Questions


Common Questions about Desonide (Desowen)


Is desonide the same as hydrocortisone?

No, desonide is not the same as hydrocortisone. However, both desonide and hydrocortisone are low-potency steroids for topical dermatologic use.



How quickly does desonide start working?

You should see improvement in your skin condition within 2-4 weeks of starting desonide treatment. Tell your doctor if you don’t see any improvement after using topical desonide cream, ointment, or lotion for 2 weeks or topical desonide foam or gel for 4 weeks.



Is DesOwen over-the-counter?

No, DesOwen (topical desonide) is not over-the-counter. You need a doctor’s prescription for this steroid medicine.



Can desonide cause acne?

Desonide and other topical corticosteroids can cause acne. If this is a concern, discuss it with your provider before starting treatment. Use desonide at the lowest dose for the shortest duration to reduce the risk of side effects like acne.



Can you use desonide on dry or sensitive skin?

Desonide can cause skin dryness and irritation. Talk to your dermatologist about other treatment options if these side effects are a concern.



What is the price of desonide without insurance?

Without insurance, desonide can be as high as $81.23, but with a free BuzzRx prescription discount coupon, you could pay as low as $14.00 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.



What is the price of desonide with insurance?

Ask your pharmacist or insurance provider for your copay price on desonide—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for desonide. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.