Diphenhydramine

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Dec 12, 2022

Pros & Cons


Diphenhydramine Pros and Cons

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  • Diphenhydramine HCl works quickly to relieve allergy symptoms.
  • It is available over-the-counter.
  • It comes in various dosage forms for convenience.
  • There is a low-cost generic form of this medicine.

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  • Diphenhydramine can cause drowsiness and dizziness.
  • It is not the safest option for older adults (age 65 and above).
  • This medicine can cause hyperactivity in children.
  • It may not be safe for people with certain medical conditions like glaucoma and urinary problems.