Dofetilide

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Mar 20, 2025

Pros & Cons


Dofetilide (Tikosyn) Pros and Cons

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  • Dofetilide can help to achieve and maintain normal sinus rhythm in patients with atrial fibrillation and atrial flutter.
  • There is a lower-cost generic available.

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  • You need to stay in the hospital for at least 3 days when first starting dofetilide treatment.
  • It can cause certain types of life-threatening arrhythmias and requires close monitoring.
  • It may not be safe for people with renal impairment (kidney disease).