Dofetilide (Tikosyn) Side Effects

Possible side effects of dofetilide are listed below. Tell your doctor if these side effects are severe or continue after a few days. 

• Headache
• Nausea
• Back pain
• Stomach pain
• Flu-like symptoms of a respiratory tract infection
• Insomnia (difficulty falling asleep or staying asleep)
• Shortness of breath
• Chest pain

Dofetilide can also cause more serious side effects. Call your doctor immediately or seek emergency medical attention if you develop the following symptoms:

• Dizziness or fainting
• Fast, pounding, or irregular heartbeat
• Skin rash, hives, itching
• Unusual sweating
• Loss of appetite
• Severe diarrhea
• Vomiting
• Increased thirst

The above list may not include all the potential adverse effects of dofetilide. Contact your healthcare professional if your side effects are unusual or severe or do not improve over time. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.

Dofetilide (Tikosyn) Overdose: In case of an overdose of dofetilide, call your doctor immediately. You can also call the local poison control center or national poison control center at 1-800-222-1222. Call 911 if a person cannot be awakened, has trouble breathing, has collapsed, or has had a seizure.

Source: FDA