Donepezil

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Jan 25, 2024

Common Questions


Common Questions about Donepezil (Aricept)


Does donepezil work immediately?

Donepezil does not work immediately. There may be some improvement noticeable after a few days. But it can take a month or even longer for donepezil to have its full effect. Continue taking the medication even if there is no obvious improvement in Alzheimer’s symptoms at first. Talk to your doctor before discontinuing donepezil.



Why is donepezil given at night?

Donepezil is usually given at night because it can cause a slowed heartbeat and dizziness. Taking it before bedtime allows you to sleep through these side effects. But if donepezil causes bad dreams or sleep problems, you can take it in the morning.



What is the success rate of donepezil?

Studies have shown that donepezil can provide a modest improvement in cognition and behavior in people with moderate to severe Alzheimer’s disease. Approximately 40-60% of people with Alzheimer’s disease respond to this medicine.



Who should not take donepezil?

People with a known hypersensitivity (allergic reaction) to donepezil should not take this medicine. Donepezil may not be safe for people with stomach ulcers, seizures, irregular heartbeat, urinary problems, and lung disease.



Can I drink alcohol while on donepezil?

It is best to avoid alcohol while on donepezil. Alcohol can make side effects like dizziness worse. Alcohol can also worsen the symptoms of dementia.



What is the price of donepezil without insurance?

Without insurance, donepezil can be as high as $697.90, but with a free BuzzRx prescription discount coupon, you could pay as low as $11.90 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.



What is the price of donepezil with insurance?

Ask your pharmacist or insurance provider for your copay price on donepezil—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for donepezil. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.