Drospirenone and Ethinyl Estradiol (YASMIN) Side Effects

Possible side effects of drospirenone and ethinyl estradiol are listed below. Tell your healthcare provider if these side effects are severe or do not go away in a few days.

• Premenstrual syndrome (PMS)
• Headache
• Breast tenderness
• Nausea, vomiting
• Spotting or irregular menstrual cycles
• Weight gain

More serious side effects of drospirenone and ethinyl estradiol are listed below. Call your doctor immediately or seek emergency medical care if you experience:

• Skin rash, hives, itching, or swelling of the face, lips, tongue, or throat (signs of an allergic reaction)
• Severe stomach pain, nausea, vomiting, fever (signs of gallbladder problems)
• Stomach pain, loss of appetite, light colored stools, dark urine, yellowing of skin or eyes, weakness, tiredness (signs of liver injury)
• Sudden numbness or weakness on one side of the body, trouble speaking, trouble walking, dizziness, confusion, vision changes (signs of a stroke)
• Leg pain, swelling, warmth, shortness of breath (signs of a blood clot)
• Depression
• Heavy menstrual bleeding or bleeding that lasts for more than 7 days

The above list may not include all the potential adverse effects of drospirenone and ethinyl estradiol. Contact your healthcare professional if your side effects are unusual or severe or they do not get better over time. You can also report unusual side effects to the Food and Drug Administration at 1-800-FDA-1088.

Drospirenone and ethinyl estradiol Overdose: In case of an overdose of drospirenone and ethinyl estradiol, call your doctor immediately. You can also call the local poison control center or national poison control center at 1-800-222-1222. If a person cannot be awakened, has trouble breathing, has collapsed, or has had a seizure, call 911.

Source: FDA