Warnings


What may interact with DUAVEE?


-aromatase inhibitors like aminoglutethimide, anastrozole, exemestane, letrozole, testolactone
-metyrapone

This medicine may also interact with the following medications:

-barbiturates, such as phenobarbital
-carbamazepine
-clarithromycin
-erythromycin
-grapefruit juice
-medicines for fungal infections like ketoconazole and itraconazole
-phenytoin
-rifampin
-ritonavir
-St. John''s Wort
-thyroid hormones

What should I tell my health care provider before I take DUAVEE?

They need to know if you have any of these conditions:

-abnormal vaginal bleeding
-blood vessel disease or blood clots
-breast, cervical, endometrial, ovarian, liver, or uterine cancer
-dementia
-diabetes
-endometriosis
-fibroids
-gallbladder disease
-heart disease or recent heart attack
-hereditary angioedema
-high blood pressure
-high cholesterol
-high level of calcium in the blood
-kidney disease
-liver disease
-mental depression
-migraine headaches
-porphyria
-protein C deficiency
-protein S deficiency
-seizure disorder
-stroke
-systemic lupus erythematosus
-thyroid disorder
-tobacco smoker
-an unusual or allergic reaction to estrogens, bazedoxifene, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

What should I watch for while using DUAVEE?

Do not take a progestin product or additional estrogen or estrogen-like products while taking this drug. Discuss the risks and benefits of taking this drug with your prescriber.

Visit your health care professional for regular checks on your progress. You will need a regular breast and pelvic exam and Pap smear while on this medicine. You should also discuss the need for regular mammograms with your health care professional, and follow his or her guidelines for these tests.

This medicine can make your body retain fluid, making your fingers, hands, or ankles swell. Your blood pressure can go up. Contact your doctor or health care professional if you feel you are retaining fluid.

You should make sure you get enough calcium and vitamin D in your diet while you are taking this medicine. Discuss your dietary needs with your health care professional or nutritionist.

Exercise may help to prevent bone loss. Discuss your exercise needs with your doctor or health care professional.

This medicine can rarely cause blood clots. You should avoid long periods of bed rest while taking this medicine. If you are going to have surgery, tell your doctor or health care professional that you are taking this medicine. This medicine should be stopped at least 3 days before surgery. After surgery, it should be restarted only after you are walking again. It should not be restarted while you still need long periods of bed rest.

Smoking increases the risk of getting a blood clot or having a stroke while you are taking this medicine, especially if you are more than 35 years old. You are strongly advised not to smoke.

If you have any reason to think you are pregnant; stop taking this medicine at once and contact your doctor or health care professional.

If you wear contact lenses and notice visual changes, or if the lenses begin to feel uncomfortable, consult your eye care specialist.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.