What side effects may I notice from receiving Erwinase?

Side effects that you should report to your doctor or health care professional as soon as possible:

-allergic reactions (skin rash; itching or hives; swelling of the face, lips, or tongue)
-bleeding (bloody or black, tarry stools; red or dark brown urine; spitting up blood or brown material that looks like coffee grounds; red spots on the skin; unusual bruising or bleeding from the eyes, gums, or nose)
-blood clot (chest pain; shortness of breath; pain, swelling, or warmth in the leg)
-high blood sugar (increased hunger, thirst, or urination; unusually weak or tired; blurry vision)
-liver injury (dark yellow or brown urine; general ill feeling or flu-like symptoms; loss of appetite; right upper belly pain; unusually weak or tired; yellowing of the eyes or skin)
-pancreatitis (stomach pain that spreads to your back or gets worse after eating or when touched, fever, nausea, vomiting, fast heartbeat)
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

-headache
-lack or loss of appetite
-muscle pain
-mouth sores

This list may not describe all possible side effects for Erwinase. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.