Do not take this medicine with any of the following medications:

-atazanavir
-clopidogrel
-nelfinavir
-rilpivirine

This medicine may also interact with the following medications:

-antifungals like itraconazole, ketoconazole, and voriconazole
-certain antivirals for HIV or hepatitis
-certain medicines that treat or prevent blood clots like warfarin
-cilostazol
-citalopram
-dasatinib
-digoxin
-diuretics
-erlotinib
-iron supplements
-medicines for anxiety, panic, and sleep like diazepam
-medicines for seizures like carbamazepine, phenobarbital, phenytoin
-methotrexate
-mycophenolate mofetil
-nilotinib
-rifampin
-St. John''s wort
-tacrolimus
-vitamin B12

They need to know if you have any of these conditions:

-black or bloody stools
-chest pain
-difficulty swallowing
-have had heartburn for over 3 months
-have heartburn with dizziness, lightheadedness or sweating
-liver disease
-lupus
-stomach pain
-unexplained weight loss
-vomiting with blood
-wheezing
-an unusual or allergic reaction to esomeprazole, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

If you are taking this medicine without a prescription, it can take several days before your heartburn gets better. Tell your healthcare professional if your symptoms do not start to get better or if they get worse. If you need to take this medicine for more than 14 days, talk to your healthcare professional. Heartburn may sometimes be caused by a more serious condition.

If you are taking this medicine with a prescription, visit your healthcare professional for regular checks on your progress. Tell your healthcare professional if your symptoms do not start to get better or if they get worse. You may need blood work done while taking this medicine.

This medicine may cause a decrease in vitamin B12. You should make sure that you get enough vitamin B12 while you are taking this medicine. Discuss the foods you eat and the vitamins you take with your health care professional.

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light and moisture. Throw away any unused medicine after the expiration date.