Do not take this medicine with any of the following medications:

-estrogens, like hormone replacement therapy or birth control pills


This medicine may also interact with the following medications:

-dietary supplements such as androstenedione or DHEA
-prasterone
-tamoxifen

They need to know if you have any of these conditions:

-high cholesterol
-liver disease
-osteoporosis (weak bones)
-an unusual or allergic reaction to letrozole, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

Tell your doctor or healthcare professional if your symptoms do not start to get better or if they get worse.

Do not become pregnant while taking this medicine or for 3 weeks after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed while taking this medicine or for 3 weeks after stopping it.

This medicine may interfere with the ability to have a child. Talk with your doctor or health care professional if you are concerned about your fertility.

Using this medicine for a long time may increase your risk of low bone mass. Talk to your doctor about bone health.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells.

You may need blood work done while you are taking this medicine.

Keep out of the reach of children.

Store between 15 and 30 degrees C (59 and 86 degrees F). Throw away any unused medicine after the expiration date.