Glyburide

Medically Reviewed by Dr. Harshi Dhingra, M.D.

Last Reviewed: Aug 10, 2022

Common Questions


Common Questions about Glyburide (Micronase)


Is glyburide the same as metformin?

Glyburide and metformin are not the same. Both are oral glucose-lowering drugs. However, glyburide is a sulfonylurea that works by causing the pancreas to make more insulin. Metformin is a biguanide that works by lowering the amount of glucose made by the liver and absorbed by the intestine and by improving the body’s response to insulin.



Can you take glyburide and metformin together?

You can take glyburide and metformin together. Doctors frequently prescribe these two medicines together. Glyburide and metformin are available as a combination pill for convenience.



What is the difference between DiaBeta and Glynase?

DiaBeta is a regular or non-micronized glyburide. Glynase is micronized glyburide. Both contain the same active ingredient, glyburide, but non-micronized and micronized tablets are absorbed differently. Your doctor will prescribe regular or micronized tablets depending on your needs. In general, micronized tablets (Glynase) are smaller and better absorbed.



How long does it take for glyburide to lower blood sugar?

Glyburide lowers blood sugar anywhere from 15 to 60 minutes after taking a dose, depending on whether you are taking regular or micronized glyburide. That’s why you should take glyburide with your largest meal of the day.



Is glyburide safe for pregnant women?

Glyburide may not be the safest choice during pregnancy. If you are pregnant or planning to get pregnant, talk to your healthcare provider about the best glucose-lowering drugs that are safe for you and your baby. Also talk to your doctor about the safety of taking glyburide if you are feeding an infant breast milk.



What is the price of glyburide without insurance? 

Without insurance, glyburide can be as high as $43.99, but with a free BuzzRx prescription discount coupon, you could pay as low as $20.59 for the most common version of this medication. Use the BuzzRx drug price look-up tool to find the lowest discounted price, and be sure to enter the correct dosage, form, and quantity for the most accurate pricing. While generics tend to have the best savings, you can also use your BuzzRx card and coupons to purchase brand-name versions. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescription drugs—whether you have insurance or not.



What is the price of glyburide with insurance?

Ask your pharmacist or insurance provider for your copay price on glyburide—Copay amounts vary depending on the type of insurance plan you have and if there is a deductible to reach before prescription drug coverage begins.

You could save up to 80% on your prescription medication with a free BuzzRx discount coupon for glyburide. When using the BuzzRx lookup tool to find the price of your medicine, be sure to enter the correct dosage, form, and quantity to receive the most accurate discounted pricing. It never hurts to ask your pharmacist to try BuzzRx when filling or refilling any of your prescriptions—whether you have insurance or not.