-amiodarone
-azithromycin
-captopril
-carvedilol
-certain medications for fungal infections like ketoconazole and itraconazole
-clarithromycin
-conivaptan
-cyclosporine
-dronedarone
-eltrombopag
-erythromycin
-felodipine
-grapefruit juice
-lopinavir
-quercetin
-quinidine
-ranolazine
-ritonavir
-ticagrelor
-verapamil

They need to know if you have any of these conditions:

-immune system problems
-infection (especially a virus infection such as chickenpox, cold sores, or herpes)
-kidney disease
-low blood counts, like low white cell, platelet, or red cell counts
-lung or breathing disease, like asthma
-scarring or thickening of the lungs
-an unusual or allergic reaction to topotecan, other medicines, foods, dyes, or preservatives
-pregnant or trying to get pregnant
-breast-feeding

This drug may make you feel generally unwell. This is not uncommon, as chemotherapy can affect healthy cells as well as cancer cells. Report any side effects. Continue your course of treatment even though you feel ill unless your doctor tells you to stop.

Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. Do not treat yourself. This drug decreases your body''s ability to fight infections. Try to avoid being around people who are sick.

This medicine may increase your risk to bruise or bleed. Call your doctor or health care professional if you notice any unusual bleeding.

Be careful brushing and flossing your teeth or using a toothpick because you may get an infection or bleed more easily. If you have any dental work done, tell your dentist you are receiving this medicine.

Avoid taking products that contain aspirin, acetaminophen, ibuprofen, naproxen, or ketoprofen unless instructed by your doctor. These medicines may hide a fever.

Do not become pregnant while taking this medicine or for 6 months after stopping it. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Men should not father a child while taking this medicine and for 3 months after stopping it. There is a potential for serious side effects to an unborn child. Talk to your health care professional or pharmacist for more information. Do not breast-feed an infant while taking this medicine.

In females, this medicine may make it more difficult to get pregnant. This medicine has also caused reduced sperm counts in some men. This may interfere with the ability to father a child. You should talk to your doctor or health care professional if you are concerned about your fertility.

Keep out of the reach of children.

Store in the refrigerator between 2 and 8 degrees C (36 and 46 degrees F). Keep this medicine in the original container. Protect from light. Throw away any unused medicine after the expiration date.